Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR4 | P51679 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 2/20 | 0.38 |
| ▸ | MMP9 | P14780 | 2/20 | 0.38 |
| ▸ | MMP13 | P45452 | 2/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | MMP7 | P09237 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | PRKAA2 | P54646 | 3/20 | 0.36 |
| ▸ | GHSR | Q92847 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR1D | P28221 | 1/20 | 0.35 |
| ▸ | HTR1B | P28222 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21035072 | 1.00 | CCR4 (0.42) | CCR4MEN1KMT2AROCK2MMP1 | |
| SCHEMBL21035330 | 1.00 | CCR4 (0.42) | CCR4MEN1KMT2AROCK2MMP1 | |
| SCHEMBL21036232 | 0.92 | CCR4 (0.38) | CCR4KMT2AROCK2MMP1MMP9 | |
| SCHEMBL21036186 | 0.92 | CCR4 (0.38) | CCR4KMT2AROCK2MMP1MMP9 | |
| SCHEMBL21035093 | 0.92 | CCR4 (0.38) | CCR4KMT2AROCK2MMP1MMP9 | |
| SCHEMBL21034935 | 0.91 | CCR4 (0.42) | CCR4ROCK2MMP1MMP9MMP13 | |
| SCHEMBL21036254 | 0.88 | CCR4 (0.40) | CCR4ROCK2MMP1MMP9MMP13 | |
| SCHEMBL21035452 | 0.88 | CCR4 (0.40) | CCR4ROCK2MMP1MMP9MMP13 | |
| SCHEMBL21035531 | 0.87 | ITGB1 (0.38) | CCR4MEN1KMT2AKCNH2GHSR | |
| SCHEMBL21035112 | 0.87 | ITGB1 (0.38) | CCR4MEN1KMT2AKCNH2GHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019104011-A1 | CERAMIDE GALACTOSYLTRANSFERASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2019-05-31 | — | — | WO | disclosed |