Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR4 | P51679 | 4/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | MMP7 | P09237 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | MLNR | O43193 | 1/20 | 0.38 |
| ▸ | WNT3 | P56703 | 3/20 | 0.37 |
| ▸ | SFRP1 | Q8N474 | 3/20 | 0.37 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 2/20 | 0.37 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21035072 | 0.91 | CCR4 (0.42) | CCR4ROCK2MMP1MMP3MMP7 | |
| SCHEMBL21035343 | 0.91 | CCR4 (0.42) | CCR4ROCK2MMP1MMP3MMP7 | |
| SCHEMBL21035330 | 0.91 | CCR4 (0.42) | CCR4ROCK2MMP1MMP3MMP7 | |
| SCHEMBL21036254 | 0.91 | CCR4 (0.40) | CCR4ROCK2MMP1MMP3MMP7 | |
| SCHEMBL21035452 | 0.91 | CCR4 (0.40) | CCR4ROCK2MMP1MMP3MMP7 | |
| SCHEMBL21034971 | 0.88 | ADRB2 (0.38) | CCR4DRD4ADRB2ROCK2SCN9A | |
| SCHEMBL21035477 | 0.87 | ADRB2 (0.43) | CCR4ADRB2SCN9AMMP1MMP3 | |
| SCHEMBL21034936 | 0.87 | ADRB2 (0.43) | CCR4ADRB2SCN9AMMP1MMP3 | |
| SCHEMBL21035481 | 0.87 | ADRB2 (0.43) | CCR4ADRB2SCN9AMMP1MMP3 | |
| SCHEMBL21035570 | 0.85 | MMP1 (0.40) | SCN9AMMP1MMP3MMP7MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019104011-A1 | CERAMIDE GALACTOSYLTRANSFERASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2019-05-31 | — | — | WO | disclosed |