Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 3/20 | 0.45 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.45 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 5/20 | 0.43 |
| ▸ | ADAM17 | P78536 | 5/20 | 0.43 |
| ▸ | MMP13 | P45452 | 3/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | MMP7 | P09237 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 2/20 | 0.40 |
| ▸ | MMP2 | P08253 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | BRD2 | P25440 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21035539 | 1.00 | HCRTR1 (0.45) | HCRTR1HCRTR2KCNQ1MMP1ADAM17 | |
| SCHEMBL21035415 | 1.00 | HCRTR1 (0.45) | HCRTR1HCRTR2KCNQ1MMP1ADAM17 | |
| SCHEMBL21035394 | 0.91 | ADAM17 (0.42) | HCRTR1HCRTR2KCNQ1MMP1ADAM17 | |
| SCHEMBL21035414 | 0.91 | ADAM17 (0.42) | HCRTR1HCRTR2KCNQ1MMP1ADAM17 | |
| SCHEMBL21035537 | 0.91 | ADAM17 (0.42) | HCRTR1HCRTR2KCNQ1MMP1ADAM17 | |
| SCHEMBL21035339 | 0.89 | MMP1 (0.47) | HCRTR1HCRTR2KCNQ1MMP1ADAM17 | |
| SCHEMBL21035335 | 0.89 | MMP1 (0.47) | HCRTR1HCRTR2KCNQ1MMP1ADAM17 | |
| SCHEMBL21035336 | 0.89 | MMP1 (0.47) | HCRTR1HCRTR2KCNQ1MMP1ADAM17 | |
| SCHEMBL21035575 | 0.87 | MMP1 (0.46) | HCRTR1HCRTR2KCNQ1MMP1ADAM17 | |
| SCHEMBL21035083 | 0.87 | MMP1 (0.46) | HCRTR1HCRTR2KCNQ1MMP1ADAM17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019104011-A1 | CERAMIDE GALACTOSYLTRANSFERASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2019-05-31 | — | — | WO | disclosed |