Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
| ▸ | HTR7 | P34969 | 2/20 | 0.42 |
| ▸ | HTR5A | P47898 | 2/20 | 0.42 |
| ▸ | HTR2C | P28335 | 2/20 | 0.42 |
| ▸ | HTR1D | P28221 | 1/20 | 0.42 |
| ▸ | HTR1B | P28222 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.42 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.42 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 4/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21035317 | 1.00 | HTR1A (0.42) | HTR1AHTR7HTR5AHTR2CHTR1D | |
| SCHEMBL21034994 | 0.92 | ITGB1 (0.47) | HTR1AHTR7HTR5AHTR2CHTR1D | |
| SCHEMBL21034999 | 0.92 | ITGB1 (0.47) | HTR1AHTR7HTR5AHTR2CHTR1D | |
| SCHEMBL21034937 | 0.92 | ITGB1 (0.47) | HTR1AHTR7HTR5AHTR2CHTR1D | |
| SCHEMBL21035522 | 0.92 | MMP1 (0.43) | MMP1MMP3MMP9ADAM17ITGB1 | |
| SCHEMBL21035402 | 0.91 | MMP1 (0.43) | MMP1MMP3MMP9ADAM17HCRTR1 | |
| SCHEMBL21035318 | 0.91 | MMP1 (0.43) | MMP1MMP3MMP9ADAM17HCRTR1 | |
| SCHEMBL21035399 | 0.90 | HTR1A (0.44) | HTR1AHTR7HTR5AHTR2CHTR1D | |
| SCHEMBL21035314 | 0.90 | HTR1A (0.44) | HTR1AHTR7HTR5AHTR2CHTR1D | |
| SCHEMBL21035678 | 0.89 | ITGB1 (0.45) | HTR1AHTR7HTR5AHTR2CHTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019104011-A1 | CERAMIDE GALACTOSYLTRANSFERASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2019-05-31 | — | — | WO | disclosed |