Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 6/20 | 0.38 |
| ▸ | MMP1 | P03956 | 5/20 | 0.38 |
| ▸ | MMP13 | P45452 | 5/20 | 0.38 |
| ▸ | MMP9 | P14780 | 4/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | MMP7 | P09237 | 1/20 | 0.38 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.37 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.36 |
| ▸ | LSS | P48449 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21002005 | 1.00 | GHSR (0.38) | GHSRMMP1MMP13MMP9MMP3 | |
| SCHEMBL21002175 | 1.00 | GHSR (0.38) | GHSRMMP1MMP13MMP9MMP3 | |
| SCHEMBL21002142 | 0.93 | MMP1 (0.39) | GHSRMMP1MMP13MMP9MMP3 | |
| SCHEMBL21002097 | 0.93 | MMP1 (0.39) | GHSRMMP1MMP13MMP9MMP3 | |
| SCHEMBL21002239 | 0.93 | MMP1 (0.39) | GHSRMMP1MMP13MMP9MMP3 | |
| SCHEMBL21035305 | 0.92 | GHSR (0.41) | GHSRMMP1MMP13MMP9MMP3 | |
| SCHEMBL21014308 | 0.92 | GHSR (0.41) | GHSRMMP1MMP13MMP9MMP3 | |
| SCHEMBL21035381 | 0.92 | GHSR (0.41) | GHSRMMP1MMP13MMP9MMP3 | |
| SCHEMBL21001813 | 0.92 | GHSR (0.41) | GHSRMMP1MMP13MMP9MMP3 | |
| SCHEMBL21001853 | 0.92 | GHSR (0.41) | GHSRMMP1MMP13MMP9MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019104011-A1 | CERAMIDE GALACTOSYLTRANSFERASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2019-05-31 | — | — | WO | disclosed |