Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 8/20 | 0.41 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | LIPE | Q05469 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21035418 | 1.00 | GHSR (0.41) | GHSRADAM17MMP1ADRB2KCNQ1 | |
| SCHEMBL21035391 | 1.00 | GHSR (0.41) | GHSRADAM17MMP1ADRB2KCNQ1 | |
| Trifluoroacetic Acid SCHEMBL21002296 | 0.97 | GHSR (0.40) | GHSRADAM17MMP1ADRB2KCNQ1 | |
| SCHEMBL21035337 | 0.90 | KMT2A (0.45) | GHSRADAM17MMP1 | |
| SCHEMBL21035537 | 0.88 | ADAM17 (0.42) | ADAM17MMP1ADRB2KCNQ1HCRTR1 | |
| SCHEMBL21035394 | 0.88 | ADAM17 (0.42) | ADAM17MMP1ADRB2KCNQ1HCRTR1 | |
| SCHEMBL21035414 | 0.88 | ADAM17 (0.42) | ADAM17MMP1ADRB2KCNQ1HCRTR1 | |
| SCHEMBL21035349 | 0.88 | GHSR (0.46) | GHSRADAM17MMP1KCNQ1 | |
| SCHEMBL21035126 | 0.88 | GHSR (0.46) | GHSRADAM17MMP1KCNQ1 | |
| SCHEMBL21035578 | 0.88 | GHSR (0.46) | GHSRADAM17MMP1KCNQ1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019104011-A1 | CERAMIDE GALACTOSYLTRANSFERASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2019-05-31 | — | — | WO | disclosed |