Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP15 | Q460N3 | 2/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.43 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.43 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3548626 | 0.89 | PARP15 (0.51) | PARP15PARP10PARP2PKMALDH1A1 | |
| SCHEMBL18088475 | 0.89 | PARP15 (0.51) | PARP15PARP10PARP2PKMALDH1A1 | |
| SCHEMBL20325660 | 0.83 | PARP15 (0.54) | PARP15PARP10PARP2MMP3PKM | |
| SCHEMBL20325460 | 0.82 | PARP10 (0.55) | PARP15PARP10PARP2MMP3ALDH1A1 | |
| SCHEMBL9815724 | 0.80 | PARP15 (0.49) | PARP15PARP10PARP2TDP1 | |
| SCHEMBL9815721 | 0.80 | PARP15 (0.49) | PARP15PARP10PARP2TDP1 | |
| SCHEMBL29660023 | 0.79 | RORC (0.51) | PARP15PARP10PARP2PKMALDH1A1 | |
| SCHEMBL11312939 | 0.79 | PARP15 (0.46) | PARP15PARP10PARP2SIGMAR1TDP1 | |
| SCHEMBL11312915 | 0.79 | PARP15 (0.46) | PARP15PARP10PARP2SIGMAR1TDP1 | |
| SCHEMBL11158116 | 0.78 | CYP2C9 (0.56) | ALDH1A1LMNARORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019104011-A1 | CERAMIDE GALACTOSYLTRANSFERASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2019-05-31 | — | — | WO | disclosed |