SCHEMBL21036049

SCHEMBL21036049

c1ccc(-c2ccc3c(c2)c2ccccc2c2c4ccc(-c5cccc6sc7ccccc7c56)cc4c4ccccc4c32)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F9 P00740 2/20 0.40
ALOX5 P09917 1/20 0.40
LIMK1 P53667 3/20 0.37
PIM3 Q86V86 2/20 0.36
GPR3 P46089 1/20 0.36
BRDT Q58F21 1/20 0.35
MAPT P10636 2/20 0.35
RAB9A P51151 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
ALDH1A1 P00352 1/20 0.35
HPGD P15428 1/20 0.35
MAP3K8 P41279 2/20 0.33
PTPN1 P18031 1/20 0.33
SLC9A1 P19634 1/20 0.33
MEN1 O00255 1/20 0.32
APAF1 O14727 1/20 0.32
NPC1 O15118 1/20 0.32
LMNA P02545 1/20 0.32
THRB P10828 1/20 0.32
XBP1 P17861 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21035290 0.97 F9 (0.43) F9ALOX5LIMK1PIM3GPR3
SCHEMBL25081653 0.96 ALOX5 (0.40) F9ALOX5LIMK1PIM3GPR3
SCHEMBL25140447 0.96 F9 (0.40) F9ALOX5LIMK1PIM3GPR3
SCHEMBL21036057 0.94 F9 (0.41) F9ALOX5LIMK1PIM3GPR3
SCHEMBL25081725 0.94 F9 (0.38) F9ALOX5LIMK1PIM3GPR3
SCHEMBL24609477 0.94 ALOX5 (0.41) F9ALOX5LIMK1PIM3GPR3
SCHEMBL21035289 0.94 F9 (0.38) F9ALOX5LIMK1PIM3GPR3
SCHEMBL21036047 0.94 ALOX5 (0.43) F9ALOX5LIMK1GPR3BRDT
SCHEMBL21036048 0.94 ALOX5 (0.43) F9ALOX5LIMK1GPR3BRDT
SCHEMBL21036060 0.93 F9 (0.40) F9ALOX5LIMK1PIM3GPR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190165279-A1 ORGANIC ELECTROLUMINESCENT ELEMENT JNC CORPORATION (JP) 2019-05-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190165279-A1 ORGANIC ELECTROLUMINESCENT ELEMENT TCF4, LGR4, OR51E2 F9 2520/4885ALOX5 2414/4885LIMK1 264/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.