SCHEMBL21036074

SCHEMBL21036074

c1ccc(-c2ccc3c(c2)c2ccccc2c2c4ccc(-c5cccc6c7ccccc7n(-c7ccccc7)c56)cc4c4ccccc4c32)cc1

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.42
KDM4E B2RXH2 1/20 0.42
ATM Q13315 1/20 0.42
DUSP3 P51452 1/20 0.36
KMT2A Q03164 3/20 0.35
IL1R1 P14778 1/20 0.35
MEN1 O00255 2/20 0.34
ALDH1A1 P00352 1/20 0.34
MAPT P10636 1/20 0.34
HTT P42858 1/20 0.34
RXFP1 Q9HBX9 1/20 0.33
PDE10A Q9Y233 1/20 0.33
MAPK14 Q16539 1/20 0.33
AVPR1A P37288 1/20 0.33
TSPO P30536 1/20 0.32
HDAC4 P56524 1/20 0.32
GAA P10253 1/20 0.32
RXRA P19793 1/20 0.32
RXRB P28702 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25081261 0.99 L3MBTL1 (0.41) L3MBTL1KDM4EATMDUSP3KMT2A
SCHEMBL21036045 0.97 L3MBTL1 (0.42) L3MBTL1KDM4EATMDUSP3KMT2A
SCHEMBL21036044 0.96 L3MBTL1 (0.44) L3MBTL1KDM4EATMDUSP3KMT2A
SCHEMBL21036072 0.96 L3MBTL1 (0.46) L3MBTL1KDM4EATMDUSP3KMT2A
SCHEMBL21036073 0.96 L3MBTL1 (0.46) L3MBTL1KDM4EATMDUSP3KMT2A
SCHEMBL21034896 0.95 L3MBTL1 (0.41) L3MBTL1KDM4EATMDUSP3KMT2A
SCHEMBL21035297 0.94 L3MBTL1 (0.40) L3MBTL1KDM4EATMDUSP3KMT2A
SCHEMBL25081269 0.94 L3MBTL1 (0.44) L3MBTL1KDM4EATMDUSP3KMT2A
SCHEMBL25081270 0.94 L3MBTL1 (0.44) L3MBTL1KDM4EATMDUSP3KMT2A
SCHEMBL16641534 0.93 L3MBTL1 (0.46) L3MBTL1KDM4EATMDUSP3KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190165279-A1 ORGANIC ELECTROLUMINESCENT ELEMENT JNC CORPORATION (JP) 2019-05-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190165279-A1 ORGANIC ELECTROLUMINESCENT ELEMENT TCF4, LGR4, OR51E2 L3MBTL1 834/4885KDM4E 396/4885ATM 1673/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.