Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 2/20 | 0.37 |
| ▸ | DRD4 | P21917 | 5/20 | 0.33 |
| ▸ | NOS3 | P29474 | 3/20 | 0.32 |
| ▸ | NOS1 | P29475 | 3/20 | 0.32 |
| ▸ | NOS2 | P35228 | 3/20 | 0.32 |
| ▸ | DRD2 | P14416 | 4/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 3/20 | 0.31 |
| ▸ | ACHE | P22303 | 3/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.31 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.30 |
| ▸ | BAD | Q92934 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25771764 | 1.00 | CYP11B2 (0.42) | CYP11B2SIGMAR1CES1DRD4NOS3 | |
| SCHEMBL13174599 | 0.98 | CYP11B2 (0.43) | CYP11B2SIGMAR1CES1DRD4NOS3 | |
| SCHEMBL13174575 | 0.93 | CYP11B2 (0.40) | CYP11B2SIGMAR1CES1DRD4DRD2 | |
| SCHEMBL1462378 | 0.76 | CYP11B2 (0.41) | CYP11B2SIGMAR1DRD4NOS3NOS1 | |
| SCHEMBL18649722 | 0.75 | CYP11B2 (0.38) | CYP11B2SIGMAR1CES1 | |
| SCHEMBL18649607 | 0.75 | CYP11B2 (0.38) | CYP11B2SIGMAR1CES1 | |
| SCHEMBL27191934 | 0.73 | CYP11B2 (0.42) | CYP11B2SIGMAR1NOS3NOS1NOS2 | |
| SCHEMBL21974070 | 0.73 | CYP11B2 (0.42) | CYP11B2SIGMAR1NOS3NOS1NOS2 | |
| SCHEMBL19679253 | 0.73 | BCL2L1 (0.48) | CYP11B2SIGMAR1DRD4NOS3NOS1 | |
| SCHEMBL19559654 | 0.73 | CYP11B2 (0.42) | CYP11B2SIGMAR1NOS3NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190161451-A1 | HERBICIDAL PYRIMIDINE COMPOUNDS | BASF SE (DE) | 2019-05-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190161451-A1 | HERBICIDAL PYRIMIDINE COMPOUNDS | DPYD, TYMP, DHFR | CYP11B2 2766/4885SIGMAR1 2871/4885CES1 1755/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.