Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 6/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | DRD3 | P35462 | 2/20 | 0.43 |
| ▸ | MC4R | P32245 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20994279 | 1.00 | DPP4 (0.47) | DPP4S1PR1S1PR5F10PRSS1 | |
| SCHEMBL29327391 | 0.90 | MC1R (0.51) | F10PRSS1DRD2DRD3MC4R | |
| SCHEMBL1920165 | 0.90 | MC1R (0.51) | F10PRSS1DRD2DRD3MC4R | |
| SCHEMBL1946746 | 0.89 | DRD2 (0.53) | F10PRSS1DRD2DRD3 | |
| SCHEMBL6315523 | 0.89 | DPP4 (0.61) | DPP4S1PR1S1PR5F10PRSS1 | |
| SCHEMBL28924798 | 0.88 | DPP4 (0.52) | DPP4S1PR1S1PR5DRD2DRD3 | |
| SCHEMBL4011897 | 0.88 | RORC (0.44) | F10PRSS1 | |
| SCHEMBL8685048 | 0.87 | DPP4 (0.47) | DPP4S1PR1S1PR5F10PRSS1 | |
| SCHEMBL8685043 | 0.87 | DPP4 (0.47) | DPP4S1PR1S1PR5F10PRSS1 | |
| SCHEMBL8685134 | 0.85 | S1PR1 (0.47) | DPP4S1PR1S1PR5DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3489231-B1 | PIPERAZINE DERIVATIVE | ASTELLAS PHARMA INC (JP) | 2021-06-09 | — | — | EP | disclosed |
| EP-3489231-A1 | PIPERAZINE DERIVATIVE | Astellas Pharma Inc. (JP) | 2019-05-29 | — | — | EP | disclosed |