Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 11/20 | 0.56 |
| ▸ | MEN1 | O00255 | 10/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | TNKS | O95271 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 11/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | TOP1 | P11387 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14501908 | 0.79 | MEN1 (0.60) | KMT2AMEN1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL15131095 | 0.75 | KMT2A (0.56) | KMT2AMEN1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL4489136 | 0.73 | KMT2A (0.57) | KMT2AMEN1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL14209236 | 0.72 | KMT2A (0.56) | KMT2AMEN1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL5110184 | 0.72 | MEN1 (0.52) | KMT2AMEN1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL11326239 | 0.71 | KMT2A (0.53) | KMT2AMEN1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL4497665 | 0.71 | MEN1 (0.55) | KMT2AMEN1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL4492144 | 0.70 | KMT2A (0.54) | KMT2AMEN1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL4487724 | 0.70 | KMT2A (0.54) | KMT2AMEN1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL4497379 | 0.70 | MEN1 (0.54) | KMT2AMEN1KDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10806733-B2 | Substituted benzaldehyde compounds and methods for their use in increasing tissue oxygenation | GLOBAL BLOOD THERAPEUTICS, INC. (US) | 2020-10-20 | — | — | US | disclosed |
| US-20190160060-A1 | SUBSTITUTED BENZALDEHYDE COMPOUNDS AND METHODS FOR THEIR USE IN INCREASING TISSUE OXYGENATION | GLOBAL BLOOD THERAPEUTICS, INC. | 2019-05-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10806733-B2 | Substituted benzaldehyde compounds and methods for their use in increasing tissue oxygenation | HBB, HBG2, MB | KMT2A 1436/4885MEN1 4829/4885KDM4E 863/4885 |
| US-20190160060-A1 | SUBSTITUTED BENZALDEHYDE COMPOUNDS AND METHODS FOR THEIR USE IN INCREASING TISSUE OXYGENATION | HBB, HBG2, MB | KMT2A 1436/4885MEN1 4829/4885KDM4E 863/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.