Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 8/20 | 0.55 |
| ▸ | DRD1 | P21728 | 2/20 | 0.55 |
| ▸ | DRD3 | P35462 | 8/20 | 0.53 |
| ▸ | DRD4 | P21917 | 4/20 | 0.53 |
| ▸ | HTR1A | P08908 | 1/20 | 0.52 |
| ▸ | DRD5 | P21918 | 1/20 | 0.52 |
| ▸ | HTR7 | P34969 | 1/20 | 0.52 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.52 |
| ▸ | HTR1D | P28221 | 1/20 | 0.50 |
| ▸ | HTR1B | P28222 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21029533 | 1.00 | DRD2 (0.55) | DRD2DRD1DRD3DRD4HTR1A | |
| SCHEMBL24663913 | 0.95 | DRD2 (0.52) | DRD2DRD1DRD3DRD4HTR1A | |
| SCHEMBL21039881 | 0.89 | DRD2 (0.65) | DRD2DRD1DRD3DRD4HTR1A | |
| SCHEMBL21029534 | 0.89 | DRD2 (0.65) | DRD2DRD1DRD3DRD4HTR1A | |
| SCHEMBL22694045 | 0.76 | DRD2 (0.54) | DRD2DRD1DRD3DRD4HTR1A | |
| SCHEMBL22694067 | 0.76 | DRD2 (0.53) | DRD2DRD1DRD3DRD4HTR1A | |
| SCHEMBL22703548 | 0.75 | DRD2 (0.72) | DRD2DRD1DRD3DRD4HTR1A | |
| SCHEMBL22694024 | 0.75 | DRD2 (0.52) | DRD2DRD1DRD3DRD4HTR1A | |
| SCHEMBL22703437 | 0.72 | DRD3 (0.62) | DRD2DRD1DRD3DRD4HTR1A | |
| SCHEMBL22694040 | 0.72 | DRD3 (0.62) | DRD2DRD1DRD3DRD4HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019101917-A1 | NEW CATECHOLAMINE PRODRUGS FOR USE IN THE TREATMENT OF PARKINSON'S DISEASE | H. LUNDBECK A/S (DK) | 2019-05-31 | — | — | WO | disclosed |