Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 12/20 | 0.53 |
| ▸ | DRD1 | P21728 | 2/20 | 0.53 |
| ▸ | DRD3 | P35462 | 11/20 | 0.51 |
| ▸ | DRD4 | P21917 | 4/20 | 0.51 |
| ▸ | HTR1D | P28221 | 1/20 | 0.51 |
| ▸ | HTR1B | P28222 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 2/20 | 0.50 |
| ▸ | DRD5 | P21918 | 1/20 | 0.50 |
| ▸ | HTR7 | P34969 | 1/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22694024 | 0.90 | DRD2 (0.52) | DRD2DRD1DRD3DRD4HTR1D | |
| SCHEMBL22694045 | 0.86 | DRD2 (0.54) | DRD2DRD1DRD3DRD4HTR1D | |
| SCHEMBL21040943 | 0.79 | DRD2 (0.49) | DRD2DRD1DRD3DRD4HTR1D | |
| SCHEMBL14507259 | 0.78 | DRD2 (0.47) | DRD2DRD1DRD3DRD4HTR1A | |
| SCHEMBL21029533 | 0.76 | DRD2 (0.55) | DRD2DRD1DRD3DRD4HTR1D | |
| SCHEMBL21039946 | 0.76 | DRD2 (0.55) | DRD2DRD1DRD3DRD4HTR1D | |
| SCHEMBL7790206 | 0.75 | DRD2 (0.44) | DRD2DRD1DRD3DRD4HTR1A | |
| SCHEMBL9504460 | 0.75 | HTR1A (0.50) | DRD2DRD1DRD3DRD4HTR1A | |
| Hydrochloric Acid SCHEMBL9503335 | 0.75 | HTR1A (0.48) | DRD2DRD1DRD3DRD4HTR1A | |
| SCHEMBL22703548 | 0.73 | DRD2 (0.72) | DRD2DRD1DRD3DRD4HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020234277-A1 | CATECHOLAMINE CARBAMATE PRODRUGS FOR USE IN THE TREATMENT OF PARKINSON S DISEASE | H. LUNDBECK A/S (DK) | 2020-11-26 | — | — | WO | disclosed |