Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.52 |
| ▸ | APEX1 | P27695 | 10/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 6/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | RXRG | P48443 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | AGER | Q15109 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21002161 | 1.00 | AKR1C3 (0.52) | AKR1C3APEX1TBXAS1RXRARXRB | |
| SCHEMBL21001877 | 1.00 | AKR1C3 (0.52) | AKR1C3APEX1TBXAS1RXRARXRB | |
| SCHEMBL27077555 | 0.81 | ALDH1A1 (0.36) | AKR1C3ALDH1A1KDM4ECYP3A4MAPT | |
| SCHEMBL641498 | 0.81 | AKR1C3 (0.45) | AKR1C3APEX1TBXAS1RXRARXRB | |
| SCHEMBL17368451 | 0.79 | AKR1C3 (0.44) | AKR1C3APEX1TBXAS1RXRARXRB | |
| SCHEMBL21001976 | 0.79 | ALDH1A1 (0.35) | AKR1C3ALDH1A1KDM4ECYP3A4MAPT | |
| SCHEMBL12649144 | 0.77 | TDP1 (0.34) | ALDH1A1KDM4ECYP3A4MAPTALOX15 | |
| SCHEMBL2752344 | 0.76 | AKR1C3 (0.55) | AKR1C3APEX1RXRARXRBNR4A2 | |
| SCHEMBL2752341 | 0.76 | AKR1C3 (0.55) | AKR1C3APEX1RXRARXRBNR4A2 | |
| SCHEMBL26932705 | 0.74 | KDM4E (0.36) | ALDH1A1KDM4ECYP3A4MAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200377510-A1 | DERIVATIVES OF PIPERLONGUMINE AND USES THEREOF | AURANSA INC. | 2020-12-03 | — | — | US | disclosed |
| WO-2019103897-A1 | DERIVATIVES OF PIPERLONGUMINE AND USES THEREOF | AURANSA INC. (US) | 2019-05-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200377510-A1 | DERIVATIVES OF PIPERLONGUMINE AND USES THEREOF | SHARPIN, PIR, THPO | AKR1C3 1248/4885APEX1 2256/4885TBXAS1 801/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.