SCHEMBL641498

SCHEMBL641498

CC(=Cc1ncncn1)C(=O)O

nearest known ligand 0.45

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.45
APEX1 P27695 8/20 0.39
TBXAS1 P24557 10/20 0.36
RXRA P19793 1/20 0.35
RXRB P28702 1/20 0.35
NR4A2 P43354 1/20 0.35
RXRG P48443 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21040574 0.81 AKR1C3 (0.52) AKR1C3APEX1TBXAS1RXRARXRB
SCHEMBL21001877 0.81 AKR1C3 (0.52) AKR1C3APEX1TBXAS1RXRARXRB
SCHEMBL21002161 0.81 AKR1C3 (0.52) AKR1C3APEX1TBXAS1RXRARXRB
SCHEMBL17368451 0.78 AKR1C3 (0.44) AKR1C3APEX1TBXAS1RXRARXRB
SCHEMBL27944360 0.71 AKR1C3 (0.55) AKR1C3APEX1TBXAS1RXRARXRB
SCHEMBL7268646 0.67 AKR1C3 (0.67) AKR1C3TBXAS1
SCHEMBL7963228 0.67 AKR1C3 (0.67) AKR1C3TBXAS1
SCHEMBL27224536 0.67 AKR1C3 (0.67) AKR1C3TBXAS1
SCHEMBL2462984 0.66 AKR1C3 (0.82) AKR1C3APEX1TBXAS1
SCHEMBL8746653 0.66 AKR1C3 (0.67) AKR1C3APEX1TBXAS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2112189-B1 (Meth)acrylic-modified siloxane compounds SHINETSU CHEMICAL CO (JP) 2012-02-22 EP claimed
US-11034178-B2 Thermal transfer sheet DAI NIPPON PRINTING CO., LTD. (JP) 2021-06-15 US disclosed
EP-3434495-B1 THERMAL TRANSFER SHEET DAINIPPON PRINTING CO LTD (JP) 2020-10-28 EP disclosed
US-20190143641-A1 THERMAL TRANSFER SHEET DAI NIPPON PRINTING CO., LTD. (JP) 2019-05-16 US disclosed
EP-3434495-A1 THERMAL TRANSFER SHEET Dai Nippon Printing Co., Ltd. (JP) 2019-01-30 EP disclosed
US-20180272779-A1 TRANSFER FILM DAI NIPPON PRINTING CO., LTD. (JP) 2018-09-27 US disclosed
EP-3342603-A1 TRANSFER FOIL DAI NIPPON PRINTING CO., LTD. (JP) 2018-07-04 EP disclosed
EP-3260296-A1 TRANSFER FOIL Dai Nippon Printing Co., Ltd. (JP) 2017-12-27 EP disclosed
US-20140044891-A1 OPTICAL LAMINATE NITTO DENKO CORPORATION (JP) 2014-02-13 US disclosed
US-8288493-B2 (meth)acrylic-modified siloxane compounds SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-10-16 US disclosed
US-20090270529-A1 (METH)ACRYLIC-MODIFIED SILOXANE COMPOUNDS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2009-10-29 US disclosed
US-7291400-B2 Decorative sheet DAI NIPPON PRINTING CO., LTD. (JP) 2007-11-06 US disclosed
US-20050129970-A1 Decorative sheet DAI NIPPON PRINTING CO., LTD. (JP) 2005-06-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090270529-A1 (METH)ACRYLIC-MODIFIED SILOXANE COMPOUNDS MMAB, MGMT, PAM AKR1C3 3115/4885APEX1 1120/4885TBXAS1 3070/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.