Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.39 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.38 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 4/20 | 0.36 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15539410 | 0.91 | SSTR5 (0.41) | GPR119TRPV4PARP10PARP15SCN9A | |
| SCHEMBL15538883 | 0.89 | GPR119 (0.39) | GPR119TRPV4PARP10PARP15SCN9A | |
| SCHEMBL20053644 | 0.88 | GPR119 (0.40) | GPR119TRPV4PARP10PARP15SCN9A | |
| SCHEMBL15540217 | 0.87 | GPR119 (0.42) | GPR119TRPV4PARP10PARP15SCN9A | |
| SCHEMBL18849061 | 0.86 | KDM1A (0.42) | GPR119KDM1A | |
| SCHEMBL18849091 | 0.85 | GPR119 (0.40) | GPR119KDM1A | |
| SCHEMBL21042669 | 0.85 | HCRTR2 (0.39) | GPR119TRPV4PARP10PARP15SCN9A | |
| SCHEMBL18842736 | 0.85 | SSTR5 (0.41) | GPR119TRPV4PARP10PARP15CHRM2 | |
| SCHEMBL18848866 | 0.85 | SSTR5 (0.40) | GPR119TRPV4PARP10PARP15SCN9A | |
| SCHEMBL21535174 | 0.84 | GPR119 (0.37) | GPR119TRPV4PARP10PARP15SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3074384-B1 | AMIDE DERIVATIVES FOR GPR119 AGONIST | CHONG KUN DANG PHARMACEUTICAL CORP (KR) | 2019-05-22 | — | — | EP | disclosed |