Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.39 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 2/20 | 0.39 |
| ▸ | CPS1 | P31327 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 4/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15540217 | 0.94 | GPR119 (0.42) | GPR119PARP10PARP15MTORCPS1 | |
| SCHEMBL15539702 | 0.93 | ALOX5AP (0.41) | GPR119PARP10PARP15MTORKDM1A | |
| SCHEMBL15539701 | 0.93 | ALOX5AP (0.41) | GPR119PARP10PARP15MTORKDM1A | |
| SCHEMBL18849061 | 0.92 | KDM1A (0.42) | GPR119KDM1A | |
| SCHEMBL20053732 | 0.91 | PARP10 (0.45) | GPR119PARP10PARP15MTORCPS1 | |
| SCHEMBL18849091 | 0.91 | GPR119 (0.40) | GPR119MTORKDM1A | |
| SCHEMBL15539410 | 0.90 | SSTR5 (0.41) | GPR119PARP10PARP15KCNH2TRPV4 | |
| SCHEMBL21535174 | 0.90 | GPR119 (0.37) | GPR119PARP10PARP15TRPV4KDM1A | |
| SCHEMBL21042669 | 0.89 | HCRTR2 (0.39) | GPR119PARP10PARP15CPS1HRH3 | |
| SCHEMBL20053738 | 0.89 | HRH3 (0.43) | GPR119HRH3KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3074384-B1 | AMIDE DERIVATIVES FOR GPR119 AGONIST | CHONG KUN DANG PHARMACEUTICAL CORP (KR) | 2019-05-22 | — | — | EP | disclosed |
| US-9944600-B2 | Piperidine derivatives for GPR119 agonist | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2018-04-17 | — | — | US | disclosed |