Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3116299 | 0.73 | TSHR (0.35) | TSHRALDH1A1LMNA | |
| SCHEMBL17866189 | 0.72 | TSHR (0.40) | TSHRALDH1A1LMNA | |
| Ammonia Solution, Strong SCHEMBL3116295 | 0.71 | TSHR (0.41) | TSHRALDH1A1 | |
| SCHEMBL13282214 | 0.71 | ALDH1A1 (0.40) | TSHRALDH1A1LMNA | |
| SCHEMBL20049545 | 0.70 | ALDH1A1 (0.39) | TSHRALDH1A1LMNA | |
| SCHEMBL12555775 | 0.70 | ALDH1A1 (0.39) | TSHRALDH1A1LMNA | |
| SCHEMBL12555789 | 0.70 | ALDH1A1 (0.39) | TSHRALDH1A1LMNA | |
| SCHEMBL3124527 | 0.69 | TSHR (0.34) | TSHRALDH1A1LMNA | |
| SCHEMBL29764288 | 0.68 | — | — | |
| SCHEMBL891502 | 0.68 | TSHR (0.48) | TSHRALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10301351-B2 | Stitched polypeptides | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2019-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10301351-B2 | Stitched polypeptides | VIP, IAPP, NGLY1 | TSHR 2524/4885ALDH1A1 4098/4885LMNA 3761/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.