Sugi Predict

Sugi Predict / Compounds / SCHEMBL21044540

SCHEMBL21044540

SCHEMBL21044540

COC(=O)c1cc(CI)cc(C(=O)OC)n1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPK1 P28482 3/20 0.42
▸ MAPT P10636 4/20 0.41
▸ CYP1A2 P05177 2/20 0.41
▸ GAA P10253 1/20 0.41
▸ RECQL P46063 1/20 0.41
▸ KDM4E B2RXH2 3/20 0.40
▸ ALDH1A1 P00352 3/20 0.40
▸ NPSR1 Q6W5P4 1/20 0.40
▸ NQO2 P16083 5/20 0.38
▸ GABRP O00591 1/20 0.38
▸ GABRD O14764 1/20 0.38
▸ GABRA1 P14867 1/20 0.38
▸ GABRB1 P18505 1/20 0.38
▸ GABRG2 P18507 1/20 0.38
▸ GABRB3 P28472 1/20 0.38
▸ GABRA5 P31644 1/20 0.38
▸ GABRA3 P34903 1/20 0.38
▸ GABRA2 P47869 1/20 0.38
▸ GABRB2 P47870 1/20 0.38
▸ GABRA4 P48169 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25637862 0.93 MAPK1 (0.38) MAPK1MAPTCYP1A2GAARECQL
SCHEMBL20886358 0.84 GABRP (0.46) MAPK1MAPTCYP1A2GAARECQL
SCHEMBL17911801 0.82 MAPK1 (0.43) MAPK1MAPTCYP1A2GAARECQL
SCHEMBL21044225 0.81 MAPK1 (0.42) MAPK1MAPTCYP1A2GAARECQL
SCHEMBL21044526 0.81 CYP4F2 (0.44) MAPK1MAPTCYP1A2GAARECQL
SCHEMBL21044363 0.79 CYP4A11 (0.51) MAPK1MAPTCYP1A2GAARECQL
SCHEMBL20886389 0.79 MAPK1 (0.41) MAPK1MAPTCYP1A2GAARECQL
SCHEMBL19182238 0.79 PTGS1 (0.45) MAPK1MAPTCYP1A2GAARECQL
SCHEMBL26162730 0.78 GABRP (0.42) MAPK1MAPTCYP1A2GAARECQL
SCHEMBL15894976 0.78 MAPK1 (0.46) MAPK1MAPTCYP1A2GAARECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3191451-B1 4-SUBSTITUTED PYRIDINE-2,6-DICARBOXYLIC ACID DERIVATIVES AND METHOD OF PREPARING SAME OKINAWA INST SCIENCE & TECH SCHOOL CORP (JP) 2019-06-05 — — EP claimed
US-20250346561-A1 TRACERS FOR PETROLEUM RESERVOIRS SAUDI ARABIAN OIL CO (SA) 2025-11-13 — — US disclosed
US-12410134-B2 Tracers for petroleum reservoirs SAUDI ARABIAN OIL COMPANY (SA) 2025-09-09 — — US disclosed
US-12384747-B2 Tracers for petroleum reservoirs SAUDI ARABIAN OIL COMPANY (SA) 2025-08-12 — — US disclosed
US-20240308962-A1 TRACERS FOR PETROLEUM RESERVOIRS SAUDI ARABIAN OIL COMPANY (SA) 2024-09-19 — — US disclosed
US-12077504-B2 Tracers for petroleum reservoirs SAUDI ARABIAN OIL COMPANY (SA) 2024-09-03 — — US disclosed
US-20240067606-A1 TRACERS FOR PETROLEUM RESERVOIRS SAUDI ARABIAN OIL COMPANY (SA) 2024-02-29 — — US disclosed
US-20240067606-A1 TRACERS FOR PETROLEUM RESERVOIRS SAUDI ARABIAN OIL COMPANY (SA) 2024-02-29 — — US disclosed
US-11827604-B2 Tracers for petroleum reservoirs SAUDI ARABIAN OIL COMPANY (SA) 2023-11-28 — — US disclosed
US-11827604-B2 Tracers for petroleum reservoirs SAUDI ARABIAN OIL COMPANY (SA) 2023-11-28 — — US disclosed
US-20230184099-A1 TRACERS FOR PETROLEUM RESERVOIRS SAUDI ARABIAN OIL COMPANY (SA) 2023-06-15 — — US disclosed
US-20230184099-A1 TRACERS FOR PETROLEUM RESERVOIRS SAUDI ARABIAN OIL COMPANY (SA) 2023-06-15 — — US disclosed
US-20220170363-A1 TRACERS FOR PETROLEUM RESERVOIRS SAUDI ARABIAN OIL COMPANY (SA) 2022-06-02 — — US disclosed
US-20220170363-A1 TRACERS FOR PETROLEUM RESERVOIRS SAUDI ARABIAN OIL COMPANY (SA) 2022-06-02 — — US disclosed
US-20220170362-A1 TRACERS FOR PETROLEUM RESERVOIRS SAUDI ARABIAN OIL COMPANY (SA) 2022-06-02 — — US disclosed
US-11299982-B2 Tracers for petroleum reservoirs SAUDI ARABIAN OIL COMPANY (SA) 2022-04-12 — — US disclosed
US-20190226326-A1 TRACERS FOR PETROLEUM RESERVOIRS SAUDI ARABIAN OIL COMPANY (SA) 2019-07-25 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240308962-A1 TRACERS FOR PETROLEUM RESERVOIRS TRPA1, NPC1L1, TMEM14C MAPK1 2987/4885MAPT 1129/4885CYP1A2 2637/4885
US-20220170362-A1 TRACERS FOR PETROLEUM RESERVOIRS TRPA1, NPC1L1, TMEM14C MAPK1 2987/4885MAPT 1129/4885CYP1A2 2637/4885
US-12384747-B2 Tracers for petroleum reservoirs TRPA1, NPC1L1, TMEM14C MAPK1 2987/4885MAPT 1129/4885CYP1A2 2637/4885
US-12077504-B2 Tracers for petroleum reservoirs TRPA1, NPC1L1, TMEM14C MAPK1 2959/4885MAPT 1138/4885CYP1A2 2638/4885
US-20240067606-A1 TRACERS FOR PETROLEUM RESERVOIRS TRPA1, NPC1L1, TMEM14C MAPK1 3103/4885MAPT 1138/4885CYP1A2 2660/4885
US-12410134-B2 Tracers for petroleum reservoirs TRPA1, NPC1L1, TMEM14C MAPK1 3103/4885MAPT 1138/4885CYP1A2 2660/4885
US-20190226326-A1 TRACERS FOR PETROLEUM RESERVOIRS TRPA1, NPC1L1, TMEM14C MAPK1 2959/4885MAPT 1138/4885CYP1A2 2638/4885
US-20230184099-A1 TRACERS FOR PETROLEUM RESERVOIRS TRPA1, NPC1L1, TMEM14C MAPK1 2959/4885MAPT 1138/4885CYP1A2 2638/4885
US-20250346561-A1 TRACERS FOR PETROLEUM RESERVOIRS TRPA1, NPC1L1, TMEM14C MAPK1 2987/4885MAPT 1129/4885CYP1A2 2637/4885
US-11827604-B2 Tracers for petroleum reservoirs TRPA1, NPC1L1, TMEM14C MAPK1 2987/4885MAPT 1129/4885CYP1A2 2637/4885
US-11299982-B2 Tracers for petroleum reservoirs TMEM14C, LPAR1, NPC1L1 MAPK1 2641/4885MAPT 980/4885CYP1A2 2481/4885
US-20220170363-A1 TRACERS FOR PETROLEUM RESERVOIRS TRPA1, NPC1L1, TMEM14C MAPK1 2987/4885MAPT 1129/4885CYP1A2 2637/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.