Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | PLAU | P00749 | 2/20 | 0.49 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | PLG | P00747 | 1/20 | 0.47 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.47 |
| ▸ | KLK1 | P06870 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Beta-Naphtoic Acid SCHEMBL4587290 | 0.84 | CES2 (0.68) | CES2CES1PLAUF2PLG | |
| Benzoic Acid SCHEMBL27848781 | 0.83 | TSHR (0.64) | CES2CES1POLBTSHRCYP3A4 | |
| Beta-Naphtoic Acid SCHEMBL28745133 | 0.83 | CES2 (0.61) | CES2CES1PLAUF2PLG | |
| Beta-Naphtoic Acid SCHEMBL28648266 | 0.82 | CES2 (0.65) | CES2CES1PLAUF2PLG | |
| Beta-Naphtoic Acid SCHEMBL30678322 | 0.82 | CES2 (0.71) | CES2CES1PLAUF2PLG | |
| Beta-Naphtoic Acid SCHEMBL29628843 | 0.82 | CES2 (0.71) | CES2CES1PLAUF2PLG | |
| Naphthalene SCHEMBL6439633 | 0.82 | CES2 (0.71) | CES2CES1PLAUF2PLG | |
| Beta-Naphtoic Acid SCHEMBL30678321 | 0.82 | CES2 (0.71) | CES2CES1PLAUF2PLG | |
| Beta-Naphtoic Acid SCHEMBL98296 | 0.82 | CES2 (0.71) | CES2CES1PLAUF2PLG | |
| Beta-Naphtoic Acid SCHEMBL25370444 | 0.80 | CES2 (0.68) | CES2CES1PLAUF2PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3284520-B1 | POLYCYCLIC CARBAMOYLPYRIDONE DERIVATIVE HAVING HIV INTEGRASE INHIBITORY ACTIVITY | VIIV HEALTHCARE CO (US) | 2019-06-05 | — | — | EP | disclosed |