SCHEMBL21045965

SCHEMBL21045965

c1ccc([SiH2]O[Si](O[SiH2]c2ccccc2)O[SiH2]c2ccccc2)cc1

nearest known ligand 0.30

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.30
HPGD P15428 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
MGLL Q99685 1/20 0.30
HSD17B10 Q99714 1/20 0.30
LTA4H P09960 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11518759 0.79 CA4 (0.31)
SCHEMBL3679065 0.73 TSHR (0.37) MAPTHPGDSMN1; SMN2MGLLHSD17B10
SCHEMBL11841805 0.72 MAPT (0.30) MAPTHPGDSMN1; SMN2MGLLHSD17B10
SCHEMBL5604698 0.69
SCHEMBL5470478 0.69
SCHEMBL50084 0.69
SCHEMBL179790 0.69
SCHEMBL10801938 0.67 MAPT (0.30) MAPTHPGDSMN1; SMN2MGLLHSD17B10
SCHEMBL20677886 0.67 MAPT (0.30) MAPTHPGDSMN1; SMN2MGLLHSD17B10
SCHEMBL714014 0.67 LTA4H (0.43) MAPTHPGDSMN1; SMN2MGLLHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3502181-B1 CROSSLINKED RUBBER ZEON CORP (JP) 2023-09-27 EP disclosed
US-11192975-B2 Crosslinked rubber ZEON CORPORATION (JP) 2021-12-07 US disclosed
US-10774174-B2 Use of crosslinked rubber ZEON CORPORATION (JP) 2020-09-15 US disclosed
US-20190330415-A1 USE OF CROSSLINKED RUBBER ZEON CORPORATION (JP) 2019-10-31 US disclosed
EP-3502179-A1 USE OF CROSSLINKED RUBBER Zeon Corporation (JP) 2019-06-26 EP disclosed
EP-3502181-A1 CROSSLINKED RUBBER Zeon Corporation (JP) 2019-06-26 EP disclosed
US-20190169360-A1 CROSSLINKED RUBBER ZEON CORPORATION (JP) 2019-06-06 US disclosed