Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 12/20 | 0.43 |
| ▸ | CA1 | P00915 | 9/20 | 0.43 |
| ▸ | CA9 | Q16790 | 6/20 | 0.43 |
| ▸ | CA12 | O43570 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | CCNC | P24863 | 1/20 | 0.38 |
| ▸ | CDK8 | P49336 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16935947 | 1.00 | CA2 (0.43) | CA2CA1CA9CA12ALDH1A1 | |
| SCHEMBL18551136 | 1.00 | CA2 (0.43) | CA2CA1CA9CA12ALDH1A1 | |
| SCHEMBL5409379 | 0.88 | CA2 (0.43) | CA2CA1CA9CA12ALDH1A1 | |
| SCHEMBL30761733 | 0.88 | CA2 (0.46) | CA2CA1CA9CA12ALDH1A1 | |
| SCHEMBL28346387 | 0.88 | CA2 (0.46) | CA2CA1CA9CA12ALDH1A1 | |
| SCHEMBL30761731 | 0.88 | CA2 (0.46) | CA2CA1CA9CA12ALDH1A1 | |
| SCHEMBL31155207 | 0.88 | CA2 (0.41) | CA2CA1CA9CA12ALDH1A1 | |
| SCHEMBL22952575 | 0.87 | CA2 (0.43) | CA2CA1CA9CA12ALDH1A1 | |
| SCHEMBL24391429 | 0.86 | CA2 (0.42) | CA2CA1CA9CA12ALDH1A1 | |
| SCHEMBL31628435 | 0.85 | SYK (0.41) | CA2CA1CA9CA12ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3822276-B1 | HETEROCYCLIC COMPOUND AS TRK INHIBITOR | BEIJING INNOCARE PHARMA TECH CO LTD (CN) | 2026-01-28 | — | — | EP | disclosed |
| WO-2025124460-A1 | TRICYCLIC FUSED HETEROCYCLIC PDE3/4 DUAL INHIBITOR, AND PREPARATION AND USE THEREFOR | 石家庄以岭药业股份有限公司 | 2025-06-19 | — | — | WO | disclosed |
| US-11878987-B2 | Heterocyclic compound as TRK inhibitor | BEIJING INNOCARE PHARMA TECH CO., LTD. (CN) | 2024-01-23 | — | — | US | disclosed |
| CN-116940354-A | Fused heteroaryl compounds and their use as CaMKII inhibitors | 卡都瑞恩医药股份有限公司 | 2023-10-24 | — | — | CN | disclosed |
| CN-110317214-B | Diaryl macrocycles as modulators of protein kinases | 特普医药公司 | 2022-11-22 | — | — | CN | disclosed |
| CN-110317213-B | Diaryl macrocycles as modulators of protein kinases | 特普医药公司 | 2022-10-18 | — | — | CN | disclosed |
| US-20210147445-A1 | HETEROCYCLIC COMPOUND AS TRK INHIBITOR | BEIJING INNOCARE PHARMA TECH CO., LTD. (CN) | 2021-05-20 | — | — | US | disclosed |
| EP-3822276-A1 | HETEROCYCLIC COMPOUND AS TRK INHIBITOR | Beijing InnoCare Pharma Tech Co., Ltd. (CN) | 2021-05-19 | — | — | EP | disclosed |
| US-20190169207-A1 | DIARYL MACROCYCLES AS MODULATORS OF PROTEIN KINASES | Turning Point Therapeutics, Inc. | 2019-06-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190169207-A1 | DIARYL MACROCYCLES AS MODULATORS OF PROTEIN KINASES | MAP3K20, LCK, DAPK2 | CA2 1766/4885CA1 2377/4885CA9 4029/4885 |
| US-20210147445-A1 | HETEROCYCLIC COMPOUND AS TRK INHIBITOR | NADK, NTRK3, TNNI3K | CA2 3115/4885CA1 3697/4885CA9 2460/4885 |
| US-11878987-B2 | Heterocyclic compound as TRK inhibitor | NADK, NTRK3, TNNI3K | CA2 3115/4885CA1 3697/4885CA9 2460/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.