Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 12/20 | 0.43 |
| ▸ | CA1 | P00915 | 10/20 | 0.43 |
| ▸ | CA9 | Q16790 | 7/20 | 0.43 |
| ▸ | CA12 | O43570 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.38 |
| ▸ | CCNC | P24863 | 1/20 | 0.38 |
| ▸ | CDK8 | P49336 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.37 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5409379 | 0.88 | CA2 (0.43) | CA2CA1CA9CA12ALDH1A1 | |
| SCHEMBL16935947 | 0.87 | CA2 (0.43) | CA2CA1CA9CA12ALDH1A1 | |
| SCHEMBL21046004 | 0.87 | CA2 (0.43) | CA2CA1CA9CA12ALDH1A1 | |
| SCHEMBL18551136 | 0.87 | CA2 (0.43) | CA2CA1CA9CA12ALDH1A1 | |
| SCHEMBL24391429 | 0.86 | CA2 (0.42) | CA2CA1CA9CA12ALDH1A1 | |
| SCHEMBL31628435 | 0.85 | SYK (0.41) | CA2CA1CA9CA12ALDH1A1 | |
| SCHEMBL31155207 | 0.85 | CA2 (0.41) | CA2CA1CA9CA12ALDH1A1 | |
| SCHEMBL23532131 | 0.84 | CA2 (0.40) | CA2CA1CA9CA12ALDH1A1 | |
| SCHEMBL18361551 | 0.84 | CA2 (0.40) | CA2CA1CA9CA12ALDH1A1 | |
| SCHEMBL9595198 | 0.84 | STAT3 (0.43) | CA2CA1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021022012-A1 | METHODS AND COMPOSITION FOR TREATING RESPIRATORY OBSTRUCTIVE DISEASES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-02-04 | — | — | WO | disclosed |