Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PRNP | P04156 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21046146 | 1.00 | LMNA (0.59) | LMNAKDM4EESR1CHRM1SLC6A4 | |
| SCHEMBL21046153 | 1.00 | LMNA (0.59) | LMNAKDM4EESR1CHRM1SLC6A4 | |
| SCHEMBL21046155 | 1.00 | LMNA (0.59) | LMNAKDM4EESR1CHRM1SLC6A4 | |
| SCHEMBL22166267 | 0.88 | LMNA (0.60) | LMNAKDM4EESR1CHRM1SLC6A4 | |
| SCHEMBL10825431 | 0.86 | KDM4E (0.65) | LMNAKDM4EESR1CHRM1SLC6A4 | |
| SCHEMBL10825390 | 0.86 | KDM4E (0.65) | LMNAKDM4EESR1CHRM1SLC6A4 | |
| SCHEMBL11107212 | 0.85 | KDM4E (0.67) | LMNAKDM4EESR1CHRM1SLC6A4 | |
| SCHEMBL10825355 | 0.85 | KDM4E (0.67) | LMNAKDM4EESR1CHRM1SLC6A4 | |
| SCHEMBL13020131 | 0.82 | KDM4E (0.71) | LMNAKDM4EESR1CHRM1SLC6A4 | |
| SCHEMBL14770017 | 0.82 | KDM4E (0.71) | LMNAKDM4EESR1CHRM1SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10695322-B2 | Inhibitors of bacterial growth | THE JOHNS HOPKINS UNIVERSITY (US) | 2020-06-30 | — | — | US | disclosed |
| US-20190167637-A1 | NOVEL INHIBITORS OF BACTERIAL GROWTH | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2019-06-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190167637-A1 | NOVEL INHIBITORS OF BACTERIAL GROWTH | DPEP1, PEPD, ANPEP | LMNA 3562/4885KDM4E 1353/4885ESR1 4214/4885 |
| US-10695322-B2 | Inhibitors of bacterial growth | DPEP1, PEPD, ANPEP | LMNA 3691/4885KDM4E 1171/4885ESR1 3986/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.