Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 5/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 3/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | PLAT | P00750 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19867909 | 1.00 | LNPEP (0.48) | LNPEPMAOBHRH3ALOX5CYP3A4 | |
| SCHEMBL1566108 | 0.77 | KMT2A (0.60) | MAOBALOX5SMN1; SMN2KMT2AMAOA | |
| SCHEMBL28985179 | 0.76 | LCK (0.49) | LNPEPMAOBHRH3ALOX5CYP3A4 | |
| SCHEMBL28985175 | 0.76 | LCK (0.49) | LNPEPMAOBHRH3ALOX5CYP3A4 | |
| SCHEMBL21047002 | 0.75 | LNPEP (0.40) | LNPEPMAOBHRH3ALOX5CYP3A4 | |
| SCHEMBL21047003 | 0.75 | LNPEP (0.40) | LNPEPMAOBHRH3ALOX5CYP3A4 | |
| SCHEMBL21583868 | 0.74 | TAAR1 (0.65) | MAOBSMN1; SMN2KMT2AMAOABCHE | |
| SCHEMBL2747423 | 0.74 | TAAR1 (0.65) | MAOBSMN1; SMN2KMT2AMAOABCHE | |
| SCHEMBL30211131 | 0.74 | TAAR1 (0.65) | MAOBSMN1; SMN2KMT2AMAOABCHE | |
| SCHEMBL2747426 | 0.74 | TAAR1 (0.65) | MAOBSMN1; SMN2KMT2AMAOABCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190169181-A1 | FUMAGILLOL COMPOUNDS AND METHODS OF MAKING AND USING SAME | ZAFGEN, INC. | 2019-06-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190169181-A1 | FUMAGILLOL COMPOUNDS AND METHODS OF MAKING AND USING SAME | METAP2, DNPEP, FOLH1 | LNPEP 23/4885MAOB 275/4885HRH3 2210/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.