Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FCGR3B | O75015 | 1/20 | 0.66 |
| ▸ | FCGR1A | P12314 | 1/20 | 0.66 |
| ▸ | FCGR2A | P12318 | 1/20 | 0.66 |
| ▸ | RECQL | P46063 | 2/20 | 0.56 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.56 |
| ▸ | IDH2 | P48735 | 5/20 | 0.54 |
| ▸ | KCNH3 | Q9ULD8 | 3/20 | 0.48 |
| ▸ | GBA1 | P04062 | 5/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.43 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13921814 | 0.91 | FCGR3B (0.77) | FCGR3BFCGR1AFCGR2ARECQLMCL1 | |
| SCHEMBL13421097 | 0.90 | FCGR3B (0.75) | FCGR3BFCGR1AFCGR2ARECQLMCL1 | |
| SCHEMBL13421092 | 0.88 | FCGR3B (0.81) | FCGR3BFCGR1AFCGR2ARECQLMCL1 | |
| SCHEMBL13421089 | 0.86 | FCGR3B (0.70) | FCGR3BFCGR1AFCGR2ARECQLMCL1 | |
| SCHEMBL13421330 | 0.85 | FCGR3B (0.69) | FCGR3BFCGR1AFCGR2ARECQLMCL1 | |
| SCHEMBL13921819 | 0.84 | FCGR3B (0.67) | FCGR3BFCGR1AFCGR2ARECQLMCL1 | |
| SCHEMBL13421070 | 0.84 | FCGR3B (0.71) | FCGR3BFCGR1AFCGR2ARECQLMCL1 | |
| SCHEMBL13921809 | 0.82 | FCGR3B (0.73) | FCGR3BFCGR1AFCGR2ARECQLMCL1 | |
| SCHEMBL13917187 | 0.82 | FCGR3B (0.66) | FCGR3BFCGR1AFCGR2ARECQLMCL1 | |
| SCHEMBL13921822 | 0.82 | FCGR3B (0.73) | FCGR3BFCGR1AFCGR2ARECQLMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190167576-A1 | USE OF HIGH AFFINITY MONOCLONAL ANTIBODY PRODUCT BINDERS TO INCREASE THE DURATION OF ACTION OF THERAPEUTIC MONOCLONAL ANTIBODY PRODUCTS IN A BIOLOGIC TISSUE | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2019-06-06 | — | — | US | claimed |
| US-20190167576-A1 | USE OF HIGH AFFINITY MONOCLONAL ANTIBODY PRODUCT BINDERS TO INCREASE THE DURATION OF ACTION OF THERAPEUTIC MONOCLONAL ANTIBODY PRODUCTS IN A BIOLOGIC TISSUE | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2019-06-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190167576-A1 | USE OF HIGH AFFINITY MONOCLONAL ANTIBODY PRODUCT BINDERS TO INCREASE THE DURATION OF ACTION OF THERAPEUTIC MONOCLONAL ANTIBODY PRODUCTS IN A BIOLOGIC TISSUE | FCGR2A, FCGR3B, FCGR1A | FCGR3B 2/4885FCGR1A 3/4885FCGR2A 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.