SCHEMBL21048280

SCHEMBL21048280

N#Cc1ccc(NC(=S)S)cc1C(F)(F)F

nearest known ligand 0.54

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
AR P10275 8/20 0.53
TAS2R14 Q9NYV8 1/20 0.49
SLC22A12 Q96S37 1/20 0.48
BLM P54132 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30901510 1.00 AR (0.53) ARTAS2R14SLC22A12BLM
SCHEMBL16946784 0.88 AR (0.52) ARTAS2R14SLC22A12BLM
SCHEMBL16823496 0.86 TAS2R14 (0.53) ARTAS2R14SLC22A12BLM
SCHEMBL18187538 0.85 AR (0.59) ARTAS2R14SLC22A12BLM
SCHEMBL29880411 0.85 AR (0.50) ARTAS2R14SLC22A12
SCHEMBL17651741 0.85 AR (0.50) ARTAS2R14SLC22A12
SCHEMBL2633009 0.85 AR (0.50) ARTAS2R14
SCHEMBL17657693 0.82 AR (0.48) ARTAS2R14SLC22A12
SCHEMBL17176181 0.82 L3MBTL1 (0.51) AR
SCHEMBL17658051 0.81 BLM (0.63) ARTAS2R14SLC22A12BLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3717457-B1 PROCESS FOR PREPARATION OF ENZALUTAMIDE USING NOVEL INTERMEDIATE AARTI INDUSTRIES LTD (IN) 2023-06-21 EP claimed
EP-3717457-A1 PROCESS FOR PREPARATION OF ENZALUTAMIDE USING NOVEL INTERMEDIATE Aarti Industries Limited (IN) 2020-10-07 EP claimed
CN-111386257-B Process for preparing enzalutamide using novel intermediates 阿尔第药物实验室有限公司 2024-05-24 CN disclosed
EP-3717457-B1 PROCESS FOR PREPARATION OF ENZALUTAMIDE USING NOVEL INTERMEDIATE AARTI INDUSTRIES LTD (IN) 2023-06-21 EP disclosed
EP-3717457-B1 PROCESS FOR PREPARATION OF ENZALUTAMIDE USING NOVEL INTERMEDIATE AARTI INDUSTRIES LTD (IN) 2023-06-21 EP disclosed
EP-3717457-A1 PROCESS FOR PREPARATION OF ENZALUTAMIDE USING NOVEL INTERMEDIATE Aarti Industries Limited (IN) 2020-10-07 EP disclosed
EP-3717457-A1 PROCESS FOR PREPARATION OF ENZALUTAMIDE USING NOVEL INTERMEDIATE Aarti Industries Limited (IN) 2020-10-07 EP disclosed
WO-2019106691-A1 PROCESS FOR PREPARATION OF ENZALUTAMIDE USING NOVEL INTERMEDIATE AARTI INDUSTRIES LIMITED (IN) 2019-06-06 WO disclosed