Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.59 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.50 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.44 |
| ▸ | NCS1 | P62166 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 6/20 | 0.42 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | ILK | Q13418 | 2/20 | 0.40 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.40 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.39 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.39 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19828210 | 0.83 | ALOX5 (0.53) | ALOX5DYRK1APPARAL3MBTL1MEN1 | |
| SCHEMBL9393819 | 0.79 | ALOX5 (0.61) | ALOX5DYRK1APPARAL3MBTL1MEN1 | |
| SCHEMBL9443101 | 0.79 | ALOX5 (0.64) | ALOX5DYRK1APPARAL3MBTL1MEN1 | |
| SCHEMBL30602944 | 0.78 | SMN1; SMN2 (0.59) | ALOX5DYRK1APPARAL3MBTL1CYP1A2 | |
| SCHEMBL3660244 | 0.78 | SMN1; SMN2 (0.59) | ALOX5DYRK1APPARAL3MBTL1CYP1A2 | |
| SCHEMBL10761623 | 0.77 | DYRK1A (0.60) | ALOX5DYRK1APPARAL3MBTL1MEN1 | |
| SCHEMBL17153983 | 0.77 | ALOX5 (0.52) | ALOX5DYRK1APPARAL3MBTL1MEN1 | |
| SCHEMBL10358369 | 0.77 | ALOX5 (0.62) | ALOX5DYRK1APPARAL3MBTL1MEN1 | |
| SCHEMBL3018322 | 0.76 | MAPT (0.64) | ALOX5L3MBTL1MEN1CYP1A2CYP3A4 | |
| SCHEMBL9186874 | 0.75 | ALOX5 (0.57) | ALOX5DYRK1APPARAL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10315990-B2 | Isothiocyanate compounds and isothiocyanate XPO1 protein inhibitor drugs thereof | DRIVINGFORCE THERAPEUTICS (CN) | 2019-06-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10315990-B2 | Isothiocyanate compounds and isothiocyanate XPO1 protein inhibitor drugs thereof | XPO1, XPOT, XPO4 | ALOX5 4747/4885DYRK1A 3977/4885PPARA 4002/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.