Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | PTPRC | P08575 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21048729 | 0.82 | NPC1 (0.46) | NPC1PPARAMAPTPTPRCPTPN1 | |
| SCHEMBL21048734 | 0.81 | NPC1 (0.50) | NPC1PPARAMAPTPTPRCPTPN1 | |
| SCHEMBL21048731 | 0.80 | NPC1 (0.49) | NPC1PPARAMAPTPTPRCPTPN1 | |
| SCHEMBL6702666 | 0.78 | TSHR (0.56) | NPC1MAPTPTPRCPTPN1ALDH1A1 | |
| SCHEMBL6946125 | 0.76 | ALDH1A1 (0.56) | NPC1MAPTSLC1A1ALDH1A1SMN1; SMN2 | |
| SCHEMBL31294203 | 0.76 | ALDH1A1 (0.56) | NPC1MAPTSLC1A1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9622282 | 0.76 | NPC1 (0.52) | NPC1MAPTPTPRCPTPN1ALDH1A1 | |
| SCHEMBL4545478 | 0.75 | PPARA (0.48) | NPC1PPARAMAPTPPARGALDH1A1 | |
| SCHEMBL21482516 | 0.75 | MAPT (0.48) | NPC1MAPTPTPRCPTPN1ALDH1A1 | |
| SCHEMBL1987313 | 0.75 | TSHR (0.52) | NPC1MAPTPTPRCPTPN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3141601-B1 | DOUBLE-CARBONYL REDUCTASE MUTANT AND APPLICATION OF SAME | ASYMCHEM LAB TIANJIN CO LTD (CN) | 2019-06-12 | — | — | EP | claimed |