Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 8/20 | 0.41 |
| ▸ | AOC1 | P19801 | 7/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.40 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CLK2 | P49760 | 1/20 | 0.34 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.33 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14479712 | 0.81 | MEN1 (0.40) | PTK2MEN1KMT2AHSD17B10LMNA | |
| SCHEMBL22551888 | 0.79 | AOC3 (0.48) | AOC3AOC1LOXL2CYP2E1CYP2C8 | |
| SCHEMBL19604262 | 0.79 | MEN1 (0.38) | PTK2MEN1KMT2AHSD17B10LMNA | |
| SCHEMBL29740091 | 0.78 | KMT2A (0.42) | AOC3AOC1PTK2MEN1KMT2A | |
| SCHEMBL25288602 | 0.78 | KMT2A (0.42) | AOC3AOC1PTK2MEN1KMT2A | |
| SCHEMBL11987593 | 0.78 | MEN1 (0.38) | AOC3AOC1PTK2MEN1KMT2A | |
| SCHEMBL1291311 | 0.76 | KMT2A (0.46) | PTK2MEN1KMT2AHSD17B10JAK2 | |
| SCHEMBL24497562 | 0.76 | L3MBTL1 (0.38) | PTK2MEN1KMT2AHSD17B10LMNA | |
| SCHEMBL30621311 | 0.76 | KMT2A (0.46) | PTK2MEN1KMT2AHSD17B10JAK2 | |
| Hydrochloric Acid SCHEMBL30468480 | 0.75 | KMT2A (0.45) | PTK2MEN1KMT2AHSD17B10JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3143021-B1 | PYRAZOLOPYRIDINES AND PYRAZOLOPYRIMIDINES | PFIZER (US) | 2019-06-12 | — | — | EP | disclosed |