Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PTK2 | Q05397 | 8/20 | 0.37 |
| ▸ | JAK2 | O60674 | 3/20 | 0.37 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | TYK2 | P29597 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CLK2 | P49760 | 1/20 | 0.34 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14479712 | 0.85 | MEN1 (0.40) | MEN1KMT2AHSD17B10LMNASMN1; SMN2 | |
| SCHEMBL11987593 | 0.82 | MEN1 (0.38) | MEN1KMT2AHSD17B10LMNASMN1; SMN2 | |
| SCHEMBL21048846 | 0.79 | AOC3 (0.41) | MEN1KMT2AHSD17B10LMNASMN1; SMN2 | |
| SCHEMBL21048914 | 0.75 | PTK2 (0.44) | PTK2JAK2JAK1TYK2JAK3 | |
| SCHEMBL14479716 | 0.74 | PTK2 (0.46) | MEN1KMT2AHSD17B10LMNASMN1; SMN2 | |
| SCHEMBL24497562 | 0.72 | L3MBTL1 (0.38) | MEN1KMT2AHSD17B10LMNASMN1; SMN2 | |
| SCHEMBL11987600 | 0.70 | PTK2 (0.44) | MEN1KMT2AHSD17B10LMNASMN1; SMN2 | |
| SCHEMBL29740091 | 0.70 | KMT2A (0.42) | MEN1KMT2AHSD17B10LMNASMN1; SMN2 | |
| SCHEMBL25288602 | 0.70 | KMT2A (0.42) | MEN1KMT2AHSD17B10LMNASMN1; SMN2 | |
| SCHEMBL12548513 | 0.70 | HTT (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170327485-A1 | SULFONYL AMIDE DERIVATIVES FOR THE TREATMENT OF ABNORMAL CELL GROWTH | PFIZER (US) | 2017-11-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170327485-A1 | SULFONYL AMIDE DERIVATIVES FOR THE TREATMENT OF ABNORMAL CELL GROWTH | GPR119, INSR, LYAR | MEN1 675/4885KMT2A 1327/4885HSD17B10 2756/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.