Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.39 |
| ▸ | KIF11 | P52732 | 2/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.37 |
| ▸ | FEN1 | P39748 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9478914 | 0.91 | ALDH1A1 (0.53) | CYP3A4TDP1ALDH1A1TP53PDE3B | |
| SCHEMBL10434824 | 0.82 | TDP1 (0.43) | CYP3A4TDP1ALDH1A1TP53PDE3B | |
| SCHEMBL20486024 | 0.80 | TAAR1 (0.45) | CYP3A4TDP1ALDH1A1TP53KIF11 | |
| SCHEMBL18866855 | 0.79 | TAAR1 (0.42) | CYP3A4TDP1ALDH1A1TP53TAAR1 | |
| SCHEMBL8015322 | 0.79 | NR4A2 (0.40) | TP53PTGS2PTGS1HSD17B10 | |
| SCHEMBL15681345 | 0.78 | CYP3A4 (0.40) | CYP3A4TDP1ALDH1A1TP53PTGS2 | |
| SCHEMBL25271046 | 0.77 | PTGS2 (0.42) | PDE3BPDE3APTGS2PTGS1 | |
| SCHEMBL21559836 | 0.77 | ALOX5AP (0.44) | CYP3A4TDP1ALDH1A1PDE3BPDE3A | |
| SCHEMBL25222235 | 0.77 | ALOX5AP (0.44) | CYP3A4TDP1ALDH1A1PDE3BPDE3A | |
| SCHEMBL1513625 | 0.77 | ESR1 (0.43) | CYP3A4PDE3BPDE3AKIF11HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3720852-A1 | FLUOROPHENYL SUBSTITUTED MUSCARINIC RECEPTOR LIGANDS WITH SELECTIVITY FOR M3 OVER M2 | Friedrich-Alexander-Universität Erlangen-Nürnberg (DE) | 2020-10-14 | — | — | EP | disclosed |
| US-20200308168-A1 | FLUOROPHENYL SUBSTITUTED MUSCARINIC RECEPTOR LIGANDS WITH SELECTIVITY FOR M3 OVER M2 | Friedrich-Alexander-Universität Erlangen-Nürnberg (DE) | 2020-10-01 | — | — | US | disclosed |
| US-20200305431-A1 | PROCESS FOR THE MANUFACTURE OF PYRAZOLE COMPOUNDS | SOLVAY SA (BE) | 2020-10-01 | — | — | US | disclosed |
| WO-2019110521-A1 | FLUOROPHENYL SUBSTITUTED MUSCARINIC RECEPTOR LIGANDS WITH SELECTIVITY FOR M3 OVER M2 | Friedrich-Alexander-Universität Erlangen-Nürnberg (DE) | 2019-06-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200305431-A1 | PROCESS FOR THE MANUFACTURE OF PYRAZOLE COMPOUNDS | CYP3A4, CYP3A43, CYP2E1 | CYP3A4 1/4885TDP1 2224/4885ALDH1A1 245/4885 |
| US-20200308168-A1 | FLUOROPHENYL SUBSTITUTED MUSCARINIC RECEPTOR LIGANDS WITH SELECTIVITY FOR M3 OVER M2 | CHRM2, CHRM3, CHRM5 | CYP3A4 1317/4885TDP1 3542/4885ALDH1A1 866/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.