Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 2/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | CDC7 | O00311 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | PAK4 | O96013 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | PRKACA | P17612 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.36 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.36 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30026059 | 0.89 | RAB9A (0.40) | LTA4HPTGS2BACE1CDC7JAK2 | |
| SCHEMBL511304 | 0.89 | RAB9A (0.40) | LTA4HPTGS2BACE1CDC7JAK2 | |
| SCHEMBL510584 | 0.88 | TDP1 (0.38) | LTA4HBACE1CDC7JAK2ROCK2 | |
| SCHEMBL21054463 | 0.85 | MEN1 (0.41) | KDM4ECDC7JAK2ROCK2MAP4K4 | |
| SCHEMBL1711762 | 0.85 | TDP1 (0.46) | LTA4HCDC7JAK2ROCK2MAP4K4 | |
| SCHEMBL21054520 | 0.84 | MEN1 (0.39) | KDM4ECDC7JAK2ROCK2MAP4K4 | |
| SCHEMBL513469 | 0.83 | MAP4K4 (0.38) | LTA4HCDC7JAK2ROCK2MAP4K4 | |
| SCHEMBL510412 | 0.82 | MPO (0.42) | LTA4HCDC7JAK2ROCK2MAP4K4 | |
| SCHEMBL30026275 | 0.82 | MPO (0.42) | LTA4HCDC7JAK2ROCK2MAP4K4 | |
| SCHEMBL509658 | 0.82 | MAPK1 (0.41) | LTA4HCDC7JAK2ROCK2MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111698989-B | Heterocyclic substituted pyridine derivatives as antifungal agents | 安普利克斯制药公司 | 2023-08-01 | — | — | CN | disclosed |
| EP-3720438-A1 | HETEROCYCLE SUBSTITUTED PYRIDINE DERIVATIVE ANTIFUNGAL AGENTS | Amplyx Pharmaceuticals, Inc. (US) | 2020-10-14 | — | — | EP | disclosed |
| CN-111698989-A | Heterocyclic substituted pyridine derivative antifungal agent | 安普利克斯制药公司 | 2020-09-22 | — | — | CN | disclosed |
| WO-2019113542-A1 | HETEROCYCLE SUBSTITUTED PYRIDINE DERIVATIVE ANTIFUNGAL AGENTS | AMPLYX PHARMACEUTICALS, INC. (US) | 2019-06-13 | — | — | WO | disclosed |