Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 11/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 11/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TYR | P14679 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | ESRRG | P62508 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | CNR1 | P21554 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22021551 | 0.83 | TDP1 (0.36) | CYP3A4MEN1KMT2AALOX15 | |
| SCHEMBL21054984 | 0.82 | SHBG (0.44) | SHBGESR1ESR2CYP3A4MEN1 | |
| SCHEMBL10411896 | 0.80 | SHBG (0.46) | SHBGESR1ESR2CYP3A4LMNA | |
| SCHEMBL10410139 | 0.79 | SHBG (0.44) | SHBGESR1ESR2CYP3A4MEN1 | |
| SCHEMBL25230502 | 0.76 | SHBG (0.52) | SHBGESR1ESR2CYP3A4MEN1 | |
| SCHEMBL28477537 | 0.74 | SHBG (0.68) | SHBGESR1ESR2CYP3A4MEN1 | |
| SCHEMBL10411897 | 0.73 | SHBG (0.48) | SHBGESR1ESR2CYP3A4LMNA | |
| SCHEMBL10410405 | 0.73 | SHBG (0.39) | SHBGESR1ESR2CYP3A4LMNA | |
| SCHEMBL10411816 | 0.72 | ALOX15 (0.42) | SHBGESR1ESR2CYP3A4ALOX15 | |
| SCHEMBL10411352 | 0.72 | SHBG (0.36) | SHBGESR1ESR2CYP3A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210230498-A1 | Alkylphenol Detergents | LUBRIZOL CORP (US) | 2021-07-29 | — | — | US | disclosed |
| US-20210230498-A1 | Alkylphenol Detergents | LUBRIZOL CORP (US) | 2021-07-29 | — | — | US | disclosed |
| EP-3720935-A1 | ALKYLPHENOL DETERGENTS | The Lubrizol Corporation (US) | 2020-10-14 | — | — | EP | disclosed |
| WO-2019112720-A1 | ALKYLPHENOL DETERGENTS | THE LUBRIZOL CORPORATION (US) | 2019-06-13 | — | — | WO | disclosed |
| WO-2019112720-A1 | ALKYLPHENOL DETERGENTS | THE LUBRIZOL CORPORATION (US) | 2019-06-13 | — | — | WO | disclosed |