Thiourea

Thiourea

SCHEMBL21055683

NC(N)=S.S=C(Nc1ccccc1)Nc1ccccc1

nearest known ligand 0.85

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.85
TAS2R38 P59533 2/20 0.85
HSD17B10 Q99714 2/20 0.85
CYP3A4 P08684 1/20 0.85
KMT2A Q03164 5/20 0.72
MEN1 O00255 3/20 0.72
RAB9A P51151 2/20 0.72
MAPT P10636 2/20 0.72
GAA P10253 5/20 0.70
NPC1 O15118 1/20 0.70
NOX1 Q9Y5S8 1/20 0.70
TP53 P04637 1/20 0.70
TYR P14679 1/20 0.70
TSHR P16473 1/20 0.70
MAOA P21397 2/20 0.68
MAOB P27338 2/20 0.68
LMNA P02545 2/20 0.68
PTPN7 P35236 1/20 0.60
KDM4E B2RXH2 1/20 0.59
CYP1A2 P05177 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL132620 0.92 ALDH1A1 (1.00) ALDH1A1TAS2R38HSD17B10CYP3A4KMT2A
Guanidine SCHEMBL28209417 0.91 ALDH1A1 (0.77) ALDH1A1TAS2R38HSD17B10CYP3A4KMT2A
SCHEMBL9470190 0.90 ALDH1A1 (0.94) ALDH1A1TAS2R38HSD17B10CYP3A4KMT2A
SCHEMBL8956322 0.90 ALDH1A1 (0.94) ALDH1A1TAS2R38HSD17B10CYP3A4KMT2A
SCHEMBL2316198 0.84 ALDH1A1 (0.75) ALDH1A1TAS2R38HSD17B10CYP3A4KMT2A
SCHEMBL5077463 0.84 KMT2A (1.00) ALDH1A1TAS2R38HSD17B10CYP3A4KMT2A
SCHEMBL455167 0.83 ALDH1A1 (0.73) ALDH1A1TAS2R38HSD17B10CYP3A4KMT2A
SCHEMBL9243020 0.83 ALDH1A1 (0.81) ALDH1A1TAS2R38HSD17B10CYP3A4KMT2A
Tetramethylammonium Ion SCHEMBL28514624 0.83 ALDH1A1 (0.81) ALDH1A1TAS2R38HSD17B10CYP3A4KMT2A
SCHEMBL27691142 0.83 ALDH1A1 (0.81) ALDH1A1TAS2R38HSD17B10CYP3A4KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019113082-A1 A COLLECTOR FORMULATION TO ENHANCE METAL RECOVERY IN MINING APPLICATIONS DOW GLOBAL TECHNOLOGIES LLC (US) 2019-06-13 WO disclosed