Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 1.00 |
| ▸ | MAPT | P10636 | 4/20 | 1.00 |
| ▸ | MEN1 | O00255 | 2/20 | 1.00 |
| ▸ | RAB9A | P51151 | 2/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.74 |
| ▸ | TAS2R38 | P59533 | 2/20 | 0.74 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.74 |
| ▸ | GAA | P10253 | 5/20 | 0.67 |
| ▸ | MAOA | P21397 | 2/20 | 0.67 |
| ▸ | MAOB | P27338 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | NOX1 | Q9Y5S8 | 3/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.59 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8956322 | 0.89 | ALDH1A1 (0.94) | KMT2AMAPTMEN1RAB9AALDH1A1 | |
| SCHEMBL11317515 | 0.87 | MAPT (0.76) | KMT2AMAPTMEN1RAB9AALDH1A1 | |
| SCHEMBL132620 | 0.86 | ALDH1A1 (1.00) | KMT2AMAPTMEN1RAB9AALDH1A1 | |
| SCHEMBL6814473 | 0.84 | KMT2A (0.72) | KMT2AMAPTMEN1RAB9AALDH1A1 | |
| Thiourea SCHEMBL21055683 | 0.84 | ALDH1A1 (0.85) | KMT2AMAPTMEN1RAB9AALDH1A1 | |
| SCHEMBL9470190 | 0.84 | ALDH1A1 (0.94) | KMT2AMAPTMEN1RAB9AALDH1A1 | |
| SCHEMBL27691142 | 0.82 | ALDH1A1 (0.81) | KMT2AMAPTMEN1RAB9AALDH1A1 | |
| SCHEMBL12070412 | 0.82 | MAPT (0.69) | KMT2AMAPTMEN1RAB9AALDH1A1 | |
| SCHEMBL9243020 | 0.82 | ALDH1A1 (0.81) | KMT2AMAPTMEN1RAB9AALDH1A1 | |
| SCHEMBL20057662 | 0.82 | KMT2A (0.69) | KMT2AMAPTMEN1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5236633-A | Blend of transparent polymer, thiourea and copper compounds | JUJO PAPER CO., LTD. (JP) | 1993-08-17 | — | — | US | claimed |
| US-4264710-A | AN ETHYLENICALLY UNSATURATED COMPOUND, AND A PHOTOPOLYMERIZATION INIATOR | FUJI PHOTO FILM CO., LTD. (JP) | 1981-04-28 | — | — | US | claimed |
| US-20110275635-A1 | SMALL MOLECULE INHIBITORS OF NADS, NAMNAT, AND NMNAT | THE UAB RESEARCH FOUNDATION (US) | 2011-11-10 | — | — | US | disclosed |
| WO-2010123591-A2 | SMALL MOLECULE INHIBITORS OF NADS, NAMNAT, AND NMNAT | THE UAB RESEARCH FOUNDATION (US) | 2010-10-28 | — | — | WO | disclosed |
| US-20080227895-A1 | Fire retardant vinyl chloride-based resin composition and molded article thereof | MITSUBISHI PLASTICS, INC. (JP) | 2008-09-18 | — | — | US | disclosed |
| US-20060014874-A1 | Flame-resistant vinyl chlorride based resin composition and formed product therefrom | MITSUBISHI PLASTICS, INC. (JP) | 2006-01-19 | — | — | US | disclosed |
| EP-1137632-B1 | THIOUREA INHIBITORS OF HERPES VIRUSES | WYETH CORP (US) | 2004-07-28 | — | — | EP | disclosed |
| EP-1137645-B1 | ALPHA-METHYLBENZYL-CONTAINING THIOUREA INHIBITORS OF HERPES VIRUSES CONTAINING A PHENYLENEDIAMINE GROUP | WYETH CORP (US) | 2004-05-26 | — | — | EP | disclosed |
| US-6555561-B2 | N-(5-((((5-Chloro-2,4-dimethoxyphenyl)amino)thioxomethyl)-amino)-2 -pyridinyl)-2-methylbenzamide, for example; inhibiting replication of a herpes virus | WYETH | 2003-04-29 | — | — | US | disclosed |
| US-6462055-B2 | VIRICIDES | WYETH | 2002-10-08 | — | — | US | disclosed |
| EP-1144397-A3 | HETEROCYCLIC CARBOXAMIDE-CONTAINING THIOUREA INHIBITORS OF HERPES VIRUSES CONTAINING PHENYLENEDIAMINE GROUP | Wyeth (US) | 2002-09-11 | — | — | EP | disclosed |
| WO-2000034269-A1 | THIOUREA INHIBITORS OF HERPES VIRUSES | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-06-15 | — | — | WO | disclosed |
| WO-2000034268-A1 | THIOUREA INHIBITORS OF HERPES VIRUSES | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-06-15 | — | — | WO | disclosed |
| WO-2000034260-A2 | ALPHA-METHYLBENZYL-CONTAINING THIOUREA INHIBITORS OF HERPES VIRUSES CONTAINING A PHENYLENEDIAMINE GROUP | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-06-15 | — | — | WO | disclosed |
| WO-2000034261-A2 | HETEROCYCLIC CARBOXAMIDE-CONTAINING THIOUREA INHIBITORS OF HERPES VIRUSES CONTAINING A SUBSTITUTED PHENYLENEDIAMINE GROUP | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-06-15 | — | — | WO | disclosed |
| WO-2000034238-A1 | THIOUREA INHIBITORS OF HERPES VIRUSES | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-06-15 | — | — | WO | disclosed |
| WO-2000034237-A2 | ACETAMIDE AND SUBSTITUTED ACETAMIDE-CONTAINING THIOUREA INHIBITORS OF HERPES VIRUSES | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-06-15 | — | — | WO | disclosed |
| US-5514740-A | SHEET OR FILM HAVING CUPRIC SULFIDE DISPERSED THEREIN | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1996-05-07 | — | — | US | disclosed |
| US-5393443-A | Hard-coating, heat-absorbing composition and heat-shielding substance | JUJO PAPER CO., LTD. (JP) | 1995-02-28 | — | — | US | disclosed |
| CN-1094354-A | Polycarbonate-based resin laminate of absorption near infrared ray and formed body thereof | DAICEL CHEM (JP) | 1994-11-02 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110275635-A1 | SMALL MOLECULE INHIBITORS OF NADS, NAMNAT, AND NMNAT | NAMPT, NAPRT, NNT | KMT2A 1419/4885MAPT 833/4885MEN1 889/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.