Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA4 | P22748 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 2/20 | 0.31 |
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.31 |
| ▸ | EHMT1 | Q9H9B1 | 2/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL322854 | 0.89 | LMNA (0.40) | LMNAALOX15HSD17B10ALDH1A1TSHR | |
| Acrylic Acid SCHEMBL11417537 | 0.77 | LMNA (0.48) | LMNAALOX15HSD17B10ALDH1A1TSHR | |
| Acrylic Acid SCHEMBL11402097 | 0.75 | LMNA (0.50) | LMNAALOX15HSD17B10ALDH1A1TSHR | |
| SCHEMBL327365 | 0.75 | ALDH1A1 (0.48) | LMNAALOX15HSD17B10ALDH1A1 | |
| Acrylic Acid SCHEMBL5161459 | 0.75 | LMNA (0.50) | LMNAALOX15HSD17B10ALDH1A1TSHR | |
| Acrylic Acid SCHEMBL20335173 | 0.74 | LMNA (0.56) | LMNAALOX15HSD17B10ALDH1A1TSHR | |
| Acrylic Acid SCHEMBL2413568 | 0.74 | LMNA (0.56) | LMNAALOX15HSD17B10ALDH1A1TSHR | |
| Acrylic Acid SCHEMBL1403603 | 0.74 | LMNA (0.56) | LMNAALOX15HSD17B10ALDH1A1TSHR | |
| Acrylic Acid SCHEMBL1147986 | 0.72 | — | — | |
| Acrylic Acid SCHEMBL6557843 | 0.72 | LMNA (0.71) | LMNAALOX15HSD17B10ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3498695-B1 | METHOD FOR SYNTHESIZING 3-(DIFLUOROMETHYL)-1-METHYL-1H-PYRAZOLE-4-CARBOXYLIC ACID | ZHEJIANG YONGTAI TECHNOLOGY CO LTD (CN) | 2020-12-09 | — | — | EP | disclosed |
| US-10556868-B2 | Method for synthesizing 3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid and intermediates thereof | ZHEJIANG YONGTAI TECHNOLOGY CO., LTD. (CN) | 2020-02-11 | — | — | US | disclosed |
| US-20190202791-A1 | METHOD FOR SYNTHESIZING 3-(DIFLUOROMETHYL)-1-METHYL-1H-PYRAZOLE-4-CARBOXYLIC ACID AND INTERMEDIATES THEREOF | ZHEJIANG YONGTAI TECHNOLOGY CO., LTD. (CN) | 2019-07-04 | — | — | US | disclosed |
| EP-3498695-A1 | METHOD FOR SYNTHESIZING 3-(DIFLUOROMETHYL)-1-METHYL-1H-PYRAZOLE-4-CARBOXYLIC ACID, AND INTERMEDIATES THEREOF | Zhejiang Yongtai Technology Co., Ltd. (CN) | 2019-06-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190202791-A1 | METHOD FOR SYNTHESIZING 3-(DIFLUOROMETHYL)-1-METHYL-1H-PYRAZOLE-4-CARBOXYLIC ACID AND INTERMEDIATES THEREOF | AFF4, AFF1, AFF2 | LMNA 2891/4885ALOX15 1424/4885HSD17B10 3551/4885 |
| US-10556868-B2 | Method for synthesizing 3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid and intermediates thereof | AFF1, AFF4, AFF2 | LMNA 3064/4885ALOX15 1370/4885HSD17B10 3466/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.