Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.59 |
| ▸ | DRD2 | P14416 | 1/20 | 0.58 |
| ▸ | HTR2A | P28223 | 1/20 | 0.58 |
| ▸ | HTR2B | P41595 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30051979 | 0.89 | MAPT (0.67) | POLBDRD2HTR2AHTR2BKMT2A | |
| Benzoic Acid SCHEMBL21485061 | 0.88 | POLB (0.53) | POLBDRD2HTR2AHTR2BKMT2A | |
| SCHEMBL10363338 | 0.85 | POLB (0.58) | POLBDRD2HTR2AHTR2BKMT2A | |
| SCHEMBL6771410 | 0.83 | POLB (0.59) | POLBDRD2HTR2AHTR2BKMT2A | |
| SCHEMBL10362759 | 0.82 | ATM (0.46) | POLBDRD2HTR2AHTR2BKMT2A | |
| Lidamidine SCHEMBL122710 | 0.81 | POLB (0.58) | POLBDRD2HTR2AHTR2BKMT2A | |
| SCHEMBL15897563 | 0.81 | DRD2 (0.61) | POLBDRD2HTR2AHTR2BKMT2A | |
| SCHEMBL8420576 | 0.81 | POLB (0.58) | POLBDRD2HTR2AHTR2BKMT2A | |
| SCHEMBL15897760 | 0.81 | POLB (0.58) | POLBDRD2HTR2AHTR2BKMT2A | |
| Lidamidine SCHEMBL637088 | 0.80 | PKM (0.58) | POLBDRD2HTR2AHTR2BKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3496764-A1 | PRODUCTION OF BITTER PRINCIPLE DERIVATIVES | Julius-Maximilians-Universitaet Wuerzburg (DE) | 2019-06-19 | — | — | EP | disclosed |