SCHEMBL21056162

SCHEMBL21056162

CC(C)C(C)C.CCCc1ccccc1

nearest known ligand 0.80

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 7/20 0.53
TAAR1 Q96RJ0 3/20 0.50
ATM Q13315 1/20 0.50
TP53 P04637 1/20 0.48
ALDH1A1 P00352 1/20 0.46
HPGD P15428 1/20 0.46
ALOX15 P16050 1/20 0.46
ALOX12 P18054 1/20 0.46
CASP1 P29466 1/20 0.46
HSD17B10 Q99714 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.45
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
TRPA1 O75762 1/20 0.45
MAOA P21397 1/20 0.44
SLC6A2 P23975 1/20 0.44
SLC6A4 P31645 1/20 0.44
SLC6A3 Q01959 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11594885 0.89 TP53 (0.58) SIGMAR1TAAR1ATMTP53ALDH1A1
Benzene SCHEMBL28308118 0.89 TP53 (0.58) SIGMAR1TAAR1ATMTP53ALDH1A1
Benzene SCHEMBL3223041 0.89 TP53 (0.58) SIGMAR1TAAR1ATMTP53ALDH1A1
SCHEMBL40575 0.89
Isopropyl Alcohol SCHEMBL28164596 0.88 SIGMAR1 (0.51) SIGMAR1TP53ALDH1A1HPGDALOX15
Isopropylamine SCHEMBL8828022 0.88 TAAR1 (0.54) SIGMAR1TAAR1TP53MAOASLC6A2
Bromide SCHEMBL7216374 0.87 TP53 (0.55) SIGMAR1TAAR1ATMTP53ALDH1A1
Hydrochloric Acid SCHEMBL5792976 0.87 TP53 (0.55) SIGMAR1TAAR1ATMTP53ALDH1A1
SCHEMBL19066702 0.87 TAAR1 (0.56) SIGMAR1TAAR1ATMALDH1A1HPGD
Ammonia Solution, Strong SCHEMBL479482 0.87 TP53 (0.55) SIGMAR1TAAR1ATMTP53ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3497073-A1 METHOD OF STARTING UP A REACTOR FOR THE OXIDATIVE DEHYDROGENATION OF N-BUTENES BASF SE (DE) 2019-06-19 EP disclosed