Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | NR3C1 | P04150 | 7/20 | 0.47 |
| ▸ | KDR | P35968 | 10/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 9/20 | 0.46 |
| ▸ | ABL1 | P00519 | 9/20 | 0.46 |
| ▸ | EGFR | P00533 | 9/20 | 0.46 |
| ▸ | HCK | P08631 | 9/20 | 0.46 |
| ▸ | SRC | P12931 | 9/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 9/20 | 0.46 |
| ▸ | PIK3CB | P42338 | 9/20 | 0.46 |
| ▸ | MTOR | P42345 | 9/20 | 0.46 |
| ▸ | PIK3CG | P48736 | 9/20 | 0.46 |
| ▸ | EPHB4 | P54760 | 9/20 | 0.46 |
| ▸ | PRKDC | P78527 | 9/20 | 0.46 |
| ▸ | PI4KB | Q9UBF8 | 6/20 | 0.46 |
| ▸ | RET | P07949 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19871051 | 0.84 | RET (0.56) | KDM4EALDH1A1HSD17B10KDRPIK3CD | |
| SCHEMBL21540336 | 0.82 | PIK3CD (0.56) | KDRPIK3CDABL1EGFRHCK | |
| SCHEMBL17966359 | 0.80 | CYP2C19 (0.43) | ALDH1A1HSD17B10NR3C1EGFRPI4KB | |
| SCHEMBL21057281 | 0.79 | KDR (0.43) | NR3C1KDRPIK3CDABL1EGFR | |
| SCHEMBL31194551 | 0.78 | ALDH1A1 (0.57) | KDM4EALDH1A1HSD17B10NR3C1 | |
| SCHEMBL31194579 | 0.76 | KDM4E (0.55) | KDM4EALDH1A1HSD17B10NR3C1KDR | |
| SCHEMBL24096479 | 0.75 | SRC (0.61) | KDRPIK3CDABL1EGFRHCK | |
| SCHEMBL1128411 | 0.75 | NR3C1 (0.49) | NR3C1 | |
| SCHEMBL27834955 | 0.75 | NR3C1 (0.38) | NR3C1 | |
| SCHEMBL14617751 | 0.75 | PIK3CD (0.45) | KDRPIK3CDABL1EGFRHCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3505171-A1 | BICYCLIC NITROGENATED HETEROCYCLIC COMPOUND | Mitsubishi Tanabe Pharma Corporation (JP) | 2019-07-03 | — | — | EP | disclosed |
| EP-3505171-A1 | BICYCLIC NITROGENATED HETEROCYCLIC COMPOUND | Mitsubishi Tanabe Pharma Corporation (JP) | 2019-07-03 | — | — | EP | disclosed |
| US-20190185479-A1 | BICYCLIC NITROGENATED HETEROCYCLIC COMPOUND | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2019-06-20 | — | — | US | disclosed |
| US-20190185479-A1 | BICYCLIC NITROGENATED HETEROCYCLIC COMPOUND | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2019-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190185479-A1 | BICYCLIC NITROGENATED HETEROCYCLIC COMPOUND | PDE7B, PDE3A, PDE7A | KDM4E 1221/4885ALDH1A1 1644/4885HSD17B10 883/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.