SCHEMBL21059244

SCHEMBL21059244

CCCCCCOC(=O)NC(C)(C)C

nearest known ligand 0.63

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.63
ACHE P22303 12/20 0.56
NAAA Q02083 1/20 0.52
FAAH O00519 1/20 0.47
TSHR P16473 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27577278 1.00 EPHX1 (0.63) EPHX1ACHENAAAFAAHTSHR
SCHEMBL21059108 0.98 EPHX1 (0.60) EPHX1ACHENAAAFAAH
SCHEMBL11100479 0.92 EPHX1 (0.52) EPHX1ACHETSHR
Ammonia Solution, Strong SCHEMBL27626603 0.90 EPHX1 (0.50) EPHX1ACHETSHR
SCHEMBL28042098 0.85 ACHE (0.54) EPHX1ACHE
SCHEMBL28212419 0.85 ACHE (0.54) EPHX1ACHE
SCHEMBL21016721 0.84 ACHE (0.42) EPHX1ACHE
SCHEMBL28164500 0.83 EPHX1 (0.45) EPHX1ACHEFAAH
SCHEMBL21596988 0.83 EPHX1 (0.43) EPHX1ACHEFAAH
SCHEMBL27684736 0.83 EPHX1 (0.43) EPHX1ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101597286-A A kind of organic catalyst and preparation thereof that contains primary amine, tertiary amine and urea or thiocarbamide DALIAN CHEMICAL PHYSICS INST (CN) 2009-12-09 CN claimed
EP-3508473-B1 METHOD FOR PRODUCING CARBAMIC ACID ESTER AIST (JP) 2021-05-26 EP disclosed
US-10752579-B2 Production method of carbamic acid ester NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2020-08-25 US disclosed
CN-110115365-A The adjusting that actinism receptor and relative ligand are carried out 西诺米克斯公司 2019-08-13 CN disclosed
CN-110062753-A Antiviral compounds 哈普洛根有限责任公司 2019-07-26 CN disclosed
EP-3508473-A1 METHOD FOR PRODUCING CARBAMIC ACID ESTER National Institute of Advanced Industrial Science and Technology (JP) 2019-07-10 EP disclosed
US-20190185420-A1 PRODUCTION METHOD OF CARBAMIC ACID ESTER NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2019-06-20 US disclosed
CN-105452238-A Bicyclic derivatives containing a pyrimidine ring and process for preparing the same YUHAN CORP 2016-03-30 CN disclosed
CN-104159891-A Pyridazine amide compounds and their use as SYK inhibitors HOFFMANN LA ROCHE 2014-11-19 CN disclosed
CN-103153096-A Methods of improving the stability of sweetness enhancers and compositions comprising stable sweetness enhancers SENOMYX INC 2013-06-12 CN disclosed
CN-102958935-A Macrocyclic integrase inhibitors TIBOTEC PHARM LTD 2013-03-06 CN disclosed
CN-102300462-A Inhibitors Of Hcv Ns5a 2011-12-28 CN disclosed
CN-102227412-A Fungicide hydroxyimino-heterocyclic derivatives BAYER CROPSCIENCE AG 2011-10-26 CN disclosed
CN-102216308-A [4- (1-amino-ethyl) -cyclohexyl] -methyl-amines as antibacterials ASTRAZENECA AB 2011-10-12 CN disclosed
CN-102015717-A Chemokine receptor modulators ALTIRIS THERAPEUTICS 2011-04-13 CN disclosed
CN-101779124-A modulation of chemosensory receptors and ligands associated therewith SENOMYX INC 2010-07-14 CN disclosed
CN-101597286-A A kind of organic catalyst and preparation thereof that contains primary amine, tertiary amine and urea or thiocarbamide DALIAN CHEMICAL PHYSICS INST (CN) 2009-12-09 CN disclosed
CN-101534904-A BCL inhibitors for the treatment of platelet excess ABBOTT LAB (US) 2009-09-16 CN disclosed
CN-101171230-A Heterocyclic-substituted alkanamides useful as renin inhibitors SPEEDEL EXPERIMENTA AG (CH) 2008-04-30 CN disclosed
CN-1348442-A Novel sulfonamide compounds and uses thereof MERCK & CO INC (US) 2002-05-08 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190185420-A1 PRODUCTION METHOD OF CARBAMIC ACID ESTER CA2, CA7, CA4 EPHX1 4759/4885ACHE 195/4885NAAA 15/4885
US-10752579-B2 Production method of carbamic acid ester CA2, CA7, CA4 EPHX1 4759/4885ACHE 195/4885NAAA 15/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.