SCHEMBL21060488

SCHEMBL21060488

O=C(O)COc1ccc(Br)cc1C1CC1

nearest known ligand 0.86

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PTGDR2 Q9Y5Y4 17/20 0.86
PTGDR Q13258 5/20 0.86
PTGER2 P43116 1/20 0.60
WDR5 P61964 2/20 0.56
POLB P06746 1/20 0.52
TSHR P16473 1/20 0.52
CTDSP1 Q9GZU7 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4882270 0.93 PTGDR2 (1.00) PTGDR2PTGDRPTGER2WDR5
SCHEMBL4882946 0.93 PTGDR2 (1.00) PTGDR2PTGDRPTGER2WDR5
SCHEMBL10733982 0.88 PTGDR2 (0.68) PTGDR2PTGDRPTGER2WDR5POLB
SCHEMBL17113009 0.78 PTGDR2 (0.88) PTGDR2PTGDRPTGER2
SCHEMBL1615073 0.77 PKM (0.70) PTGDR2PTGDRPOLBTSHRCTDSP1
SCHEMBL4879219 0.77 PTGDR2 (1.00) PTGDR2PTGDRPTGER2TDP1
SCHEMBL21095340 0.77 PTGDR2 (0.92) PTGDR2PTGDRPTGER2
SCHEMBL23599384 0.76 SLC6A4 (0.56) PTGDR2PTGDR
SCHEMBL3044855 0.76 PTGDR2 (0.79) PTGDR2PTGDRPOLBTSHRCTDSP1
SCHEMBL4886140 0.75 PTGDR2 (1.00) PTGDR2PTGDRPTGER2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4731200-A1 CLC-1 INHIBITORS FOR USE IN THE TREATMENT OF MULTIPLE SCLEROSIS AND NEUROMUSCULAR DISEASES NMD Pharma A/S (DK) 2026-04-29 EP claimed
WO-2024261020-A1 CLC-1 INHIBITORS FOR USE IN THE TREATMENT OF MULTIPLE SCLEROSIS AND NEUROMUSCULAR DISEASES NMD PHARMA A/S (DK) 2024-12-26 WO claimed
EP-4731200-A1 CLC-1 INHIBITORS FOR USE IN THE TREATMENT OF MULTIPLE SCLEROSIS AND NEUROMUSCULAR DISEASES NMD Pharma A/S (DK) 2026-04-29 EP disclosed
WO-2024261020-A1 CLC-1 INHIBITORS FOR USE IN THE TREATMENT OF MULTIPLE SCLEROSIS AND NEUROMUSCULAR DISEASES NMD PHARMA A/S (DK) 2024-12-26 WO disclosed
CN-111491628-B Phenoxy acids for the treatment of neuromuscular disorders NMD制药股份公司 2023-10-13 CN disclosed
EP-3723746-B1 PHENOXY ACIDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD PHARMA AS (DK) 2022-02-23 EP disclosed
EP-3723746-A1 PHENOXY ACIDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD Pharma A/S (DK) 2020-10-21 EP disclosed
CN-111491628-A Phenoxy acids for the treatment of neuromuscular disorders NMD制药股份公司 2020-08-04 CN disclosed
WO-2019115780-A1 PHENOXY ACIDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD PHARMA A/S (DK) 2019-06-20 WO disclosed
US-20190183812-A1 Compounds For The Treatment Of Neuromuscular Disorders NMD PHARMA A/S (DK) 2019-06-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190183812-A1 Compounds For The Treatment Of Neuromuscular Disorders RYR1, CACNB1, RYR2 PTGDR2 2581/4885PTGDR 2725/4885PTGER2 4084/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.