Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.70 |
| ▸ | PTGDR2 | Q9Y5Y4 | 8/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5502944 | 0.84 | PKM (0.68) | PKMPTGDR2TDP1POLBTSHR | |
| SCHEMBL3044855 | 0.84 | PTGDR2 (0.79) | PKMPTGDR2TDP1POLBTSHR | |
| SCHEMBL1369720 | 0.82 | PTGDR2 (0.64) | PKMPTGDR2TDP1POLBTSHR | |
| SCHEMBL3198632 | 0.82 | PTGDR2 (0.67) | PTGDR2TDP1POLBTSHRCTDSP1 | |
| SCHEMBL3203774 | 0.82 | PTGDR2 (0.64) | PKMPTGDR2TDP1POLBTSHR | |
| SCHEMBL511290 | 0.82 | HTR1B (0.55) | PKMPTGDR2TDP1POLBTSHR | |
| SCHEMBL3714744 | 0.82 | PKM (0.66) | PKMPTGDR2TDP1TSHRSMN1; SMN2 | |
| SCHEMBL3203787 | 0.82 | TDP1 (0.70) | PTGDR2TDP1POLBTSHRCTDSP1 | |
| SCHEMBL1369311 | 0.82 | TDP1 (0.70) | PKMPTGDR2TDP1TSHRPTGDR | |
| SCHEMBL2112042 | 0.82 | PKM (1.00) | PKMPTGDR2TDP1POLBPTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080108115-A1 | ENHANCED PRODUCTION OF TAXOL AND TAXANES BY CELL CULTURES OF TAXUS SPECIES | DFB BIOTECH, INCORPORATED (US) | 2008-05-08 | — | — | US | claimed |
| US-7264951-B1 | Enhanced production of taxol and taxanes by cell cultures of Taxus species | PHYTON, INC. (US) | 2007-09-04 | — | — | US | claimed |
| US-7015247-B2 | Ibuprofen-aspirin, hydroxymethylacylfulvene analogs and L-sugar illudin analogs | GUTTAG ALVIN | 2006-03-21 | — | — | US | claimed |
| US-20030008833-A1 | Ibuprofen-aspirin, hydroxymethylacylfulvene analogs and L-sugar illudin analogs | GUTTAG ALVIN (US) | 2003-01-09 | — | — | US | claimed |
| US-20020065254-A1 | Ibuprofen-aspirin and hydroxymethylacylfulvene analogs | GUTTAG ALVIN (US) | 2002-05-30 | — | — | US | claimed |
| CN-116715579-A | Continuous preparation method of isooctyl 2-methyl-4-chlorophenoxyacetate | 江苏永泰丰作物科学有限公司 | 2023-09-08 | — | — | CN | disclosed |
| CN-105126858-A | Magnetic nano neodymium-iron-titanium oxide ozone catalyst and preparation method and application thereof | HANGZHOU CUITE ENVIRONMENT PROT TECHNOLOGY CO LTD | 2015-12-09 | — | — | CN | disclosed |
| CN-104224781-A | 2-acylamino-3-alkoxyl substituted pyridine compounds and novel use thereof | INST MED BIOTECHNOLOGY CAMS | 2014-12-24 | — | — | CN | disclosed |
| US-20130017582-A1 | ENHANCED PRODUCTION OF TAXOL AND TAXANES BY CELL CULTURES OF TAXUS SPECIES | PHYTON HOLDINGS, LLC (US) | 2013-01-17 | — | — | US | disclosed |
| US-8338143-B2 | Enhanced production of paclitaxel and taxanes by cell cultures of Taxus species | PHYTON HOLDINGS, LLC (US) | 2012-12-25 | — | — | US | disclosed |
| US-20110086397-A1 | ENHANCED PRODUCTION OF TAXOL AND TAXANES BY CELL CULTURES OF TAXUS SPECIES | PHYTON HOLDINGS, LLC (US) | 2011-04-14 | — | — | US | disclosed |
| US-7414063-B2 | Inhibitors of Akt (protein kinase B) | ELI LILLY AND COMPANY (US) | 2008-08-19 | — | — | US | disclosed |
| EP-1398384-A1 | Enhanced production of taxanes by cell cultures of taxus species | Phyton Inc. (US) | 2004-03-17 | — | — | EP | disclosed |
| US-20030008833-A1 | Ibuprofen-aspirin, hydroxymethylacylfulvene analogs and L-sugar illudin analogs | GUTTAG ALVIN (US) | 2003-01-09 | — | — | US | disclosed |
| US-6436916-B1 | PHENOLIC ESTERS OF IBUPROFEN WITH SALICYLIC ACID OR ITS NONTOXIC SALTS USED AS ANTITUMOR AGENT | GUTTAG ALVIN (US) | 2002-08-20 | — | — | US | disclosed |
| US-20020065254-A1 | Ibuprofen-aspirin and hydroxymethylacylfulvene analogs | GUTTAG ALVIN (US) | 2002-05-30 | — | — | US | disclosed |
| EP-1126833-A2 | OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | TREGA BIOSCIENCES, INC. (US) | 2001-08-29 | — | — | EP | disclosed |
| WO-2000025768-A1 | OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | TREGA BIOSCIENCES, INC. (US) | 2000-05-11 | — | — | WO | disclosed |
| EP-0954596-A1 | ENHANCED PRODUCTION OF TAXANES BY CELL CULTURES OF $i(TAXUS) SPECIES | PHYTON, INC. (US) | 1999-11-10 | — | — | EP | disclosed |
| WO-1997044476-A1 | ENHANCED PRODUCTION OF TAXANES BY CELL CULTURES OF TAXUS SPECIES | PHYTON, INC. (US) | 1997-11-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020065254-A1 | Ibuprofen-aspirin and hydroxymethylacylfulvene analogs | PTGES3, HPGDS, PTGES | PKM 4303/4885PTGDR2 45/4885TDP1 665/4885 |
| US-20030008833-A1 | Ibuprofen-aspirin, hydroxymethylacylfulvene analogs and L-sugar illudin analogs | GALE, TPT1, HPSE | PKM 4602/4885PTGDR2 1291/4885TDP1 1530/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.