Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CTSD | P07339 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1805977 | 0.86 | RAB9A (0.64) | RAB9APOLBALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL1805971 | 0.86 | RAB9A (0.64) | RAB9APOLBALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL3258912 | 0.77 | ALDH1A1 (0.55) | RAB9APOLBALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL7528501 | 0.77 | ALDH1A1 (0.55) | RAB9APOLBALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL29032830 | 0.77 | ALDH1A1 (0.55) | RAB9APOLBALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL10369182 | 0.77 | ALDH1A1 (0.55) | RAB9APOLBALDH1A1TSHRLMNA | |
| SCHEMBL8390018 | 0.75 | ALDH1A1 (0.58) | RAB9APOLBALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL10344185 | 0.75 | ALDH1A1 (0.58) | RAB9APOLBALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL3846868 | 0.74 | MAPT (0.53) | RAB9AALDH1A1TSHRLMNASMN1; SMN2 | |
| SCHEMBL2033896 | 0.74 | ALDH1A1 (0.51) | RAB9AALDH1A1TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3724192-A1 | TRIAZOLOBENZAZEPINES AS VASOPRESSIN V1A RECEPTOR ANTAGONISTS | Richter Gedeon Nyrt. (HU) | 2020-10-21 | — | — | EP | disclosed |
| WO-2019116324-A1 | TRIAZOLOBENZAZEPINES AS VASOPRESSIN V1A RECEPTOR ANTAGONISTS | RICHTER GEDEON NYRT. (HU) | 2019-06-20 | — | — | WO | disclosed |