Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 4/20 | 0.53 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.49 |
| ▸ | CES1 | P23141 | 3/20 | 0.46 |
| ▸ | RRM1 | P23921 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.45 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5248007 | 0.98 | CES2 (0.55) | CES2DNM1CES1RRM1MEN1 | |
| SCHEMBL7777074 | 0.98 | CES2 (0.55) | CES2DNM1CES1RRM1MEN1 | |
| SCHEMBL3914545 | 0.98 | CES2 (0.55) | CES2DNM1CES1RRM1MEN1 | |
| SCHEMBL3910768 | 0.98 | CES2 (0.55) | CES2DNM1CES1RRM1MEN1 | |
| SCHEMBL2374459 | 0.98 | CES2 (0.55) | CES2DNM1CES1RRM1MEN1 | |
| Acetic Acid SCHEMBL8103185 | 0.94 | CES2 (0.48) | CES2MEN1KMT2AALDH1A1TSHR | |
| Acetic Acid SCHEMBL1987108 | 0.94 | CES2 (0.48) | CES2MEN1KMT2AALDH1A1TSHR | |
| Acetic Acid SCHEMBL21049873 | 0.94 | CES2 (0.48) | CES2MEN1KMT2AALDH1A1TSHR | |
| Acetic Acid SCHEMBL8093379 | 0.94 | CES2 (0.48) | CES2MEN1KMT2AALDH1A1TSHR | |
| Acetic Acid SCHEMBL8107130 | 0.94 | CES2 (0.48) | CES2MEN1KMT2AALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3724698-A1 | METHOD FOR PRODUCING MPS-COMPATIBLE WATER GRADIENT CONTACT LENSES | Alcon Inc. (CH) | 2020-10-21 | — | — | EP | disclosed |
| WO-2019116141-A1 | METHOD FOR PRODUCING MPS-COMPATIBLE WATER GRADIENT CONTACT LENSES | NOVARTIS AG (CH) | 2019-06-20 | — | — | WO | disclosed |