Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 known ✓ | P03372 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 5/20 | 0.45 |
| ▸ | PPARD | Q03181 | 5/20 | 0.45 |
| ▸ | PPARA | Q07869 | 5/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TLR2 | O60603 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | FABP4 | P15090 | 2/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.45 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.45 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | PDE4A | P27815 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL8093379 | 1.00 | CES2 (0.48) | CES2PPARGPPARDPPARAHDAC11 | |
| Acetic Acid SCHEMBL8107130 | 1.00 | CES2 (0.48) | CES2PPARGPPARDPPARAHDAC11 | |
| Acetic Acid SCHEMBL21049873 | 1.00 | CES2 (0.48) | CES2PPARGPPARDPPARAHDAC11 | |
| Acetic Acid SCHEMBL27505734 | 1.00 | CES2 (0.48) | CES2PPARGPPARDPPARAHDAC11 | |
| Acetic Acid SCHEMBL8103185 | 1.00 | CES2 (0.48) | CES2PPARGPPARDPPARAHDAC11 | |
| Acetic Acid SCHEMBL6261375 | 0.98 | CES2 (0.50) | CES2PPARGPPARDPPARAHDAC11 | |
| Acetic Acid SCHEMBL468672 | 0.98 | CES2 (0.50) | CES2PPARGPPARDPPARAHDAC11 | |
| Acetic Acid SCHEMBL27538125 | 0.96 | CES2 (0.48) | CES2PPARGPPARDPPARAHDAC11 | |
| Acetic Acid SCHEMBL27548987 | 0.96 | CES2 (0.48) | CES2PPARGPPARDPPARAHDAC11 | |
| SCHEMBL21061920 | 0.94 | CES2 (0.53) | CES2TSHRGPR84ALDH1A1SLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1579022-A2 | COATED METAL COMPONENTS IN AEROSOL VALVES AND DISPENSING PUMPS FOR METAL-SENSITIVE COMPOSITIONS AND PROCESS OF COATING THE COMPONENTS | AVON PRODUCTS, INC. (US) | 2005-09-28 | — | — | EP | claimed |
| US-20040265522-A1 | Coated metal components in aerosol valves and dispensing pumps for metal-sensitive compositions and process of coating the components | AVON PRODUCTS, INC. | 2004-12-30 | — | — | US | claimed |
| WO-2003023083-A2 | COATINGS FOR METAL COMPONENTS OF CONTAINER | AVON PRODUCTS, INC. (US) | 2003-03-20 | — | — | WO | claimed |
| US-5886031-A | ADMINISTERING TO A PERSON AN EFFECTIVE AMOUNT OF IODOPROPYNYL BUTYL CARBAMATE AN ANTIBACTERIAL AND ANTIDANDRUFF AGENT WITH AN ADSORPTION-ACCELERATING AGENTS SELECTED FROM UREA, GUAR HYDROXYPROPYL TRIMONIUM CHLORIDE, AND POLYQUATERNIUM-10 | PACIFIC CORPORATION (KR) | 1999-03-23 | — | — | US | claimed |
| WO-2016110872-A1 | FOOT CARE COMPOSITIONS | Zydus Wellness Limited (IN) | 2016-07-14 | — | — | WO | disclosed |
| EP-2337544-A2 | USE OF MATRIX METALLOPROTEINASE INHIBITORS IN SKIN CARE | Living Proof, Inc. (US) | 2011-06-29 | — | — | EP | disclosed |
| US-20100143274-A1 | USE OF AMINES AND AMIDES FOR THE STABILIZATION OF ORGANIC MICRONIZED UV ABSORBERS | CIBA CORPORATION (US) | 2010-06-10 | — | — | US | disclosed |
| EP-2120846-A2 | USE OF AMINES AND AMIDES FOR THE STABILIZATION OF ORGANIC MICRONIZED UV ABSORBERS | BASF SE (DE) | 2009-11-25 | — | — | EP | disclosed |
| US-20090068255-A1 | USE OF MATRIX METALLOPROTEINASE INHIBITORS IN SKIN CARE | LIVING PROOF, INC. | 2009-03-12 | — | — | US | disclosed |
| WO-2008134712-A2 | USE OF MATRIX METALLOPROTEINASE INHIBITORS IN SKIN CARE | LIVING PROOF, INC. (US) | 2008-11-06 | — | — | WO | disclosed |
| WO-2008107347-A2 | USE OF AMINES AND AMIDES FOR THE STABILIZATION OF ORGANIC MICRONIZED UV ABSORBERS | BASF SE (CH) | 2008-09-12 | — | — | WO | disclosed |
| WO-2008070368-A2 | METHODS AND COMPOSITIONS FOR SKIN CARE | LIVING PROOF, INC. (US) | 2008-06-12 | — | — | WO | disclosed |
| EP-1827361-A1 | ANTI-CARIES ORAL CARE COMPOSITION WITH A CHELATING AGENT | Colgate-Palmolive Company (US) | 2007-09-05 | — | — | EP | disclosed |
| US-20070077380-A1 | Coated metal components in aerosol valves and dispensing pumps for metal-sensitive compositions and process of coating the components | FONSECA GEOFFREY | 2007-04-05 | — | — | US | disclosed |
| WO-2006068753-A1 | ANTI-CARIES ORAL CARE COMPOSITION WITH A CHELATING AGENT | COLGATE-PALMOLIVE COMPANY (US) | 2006-06-29 | — | — | WO | disclosed |
| US-20060134020-A1 | Anti-caries oral care composition with a chelating agent | COLGATE-PALMOLIVE COMPANY | 2006-06-22 | — | — | US | disclosed |
| US-20040265522-A1 | Coated metal components in aerosol valves and dispensing pumps for metal-sensitive compositions and process of coating the components | AVON PRODUCTS, INC. | 2004-12-30 | — | — | US | disclosed |
| US-6054450-A | SOLUTION OF ZINC PYRITHIONE IN N-ACYLETHYLENEDIAMINETRIACETATE. | PACIFIC CORPORATION (KR) | 2000-04-25 | — | — | US | disclosed |
| US-5886031-A | ADMINISTERING TO A PERSON AN EFFECTIVE AMOUNT OF IODOPROPYNYL BUTYL CARBAMATE AN ANTIBACTERIAL AND ANTIDANDRUFF AGENT WITH AN ADSORPTION-ACCELERATING AGENTS SELECTED FROM UREA, GUAR HYDROXYPROPYL TRIMONIUM CHLORIDE, AND POLYQUATERNIUM-10 | PACIFIC CORPORATION (KR) | 1999-03-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090068255-A1 | USE OF MATRIX METALLOPROTEINASE INHIBITORS IN SKIN CARE | MMP1, MMP9, MMP17 | ESR1 3045/4885CES2 2512/4885PPARG 449/4885 |
| US-20100143274-A1 | USE OF AMINES AND AMIDES FOR THE STABILIZATION OF ORGANIC MICRONIZED UV ABSORBERS | MAOA, MAOB, ACMSD | ESR1 1513/4885CES2 1491/4885PPARG 1192/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.