Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TMIGD3 | P0DMS9 | 3/20 | 0.37 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.37 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.36 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26298195 | 0.90 | ALDH1A1 (0.37) | ALDH1A1KMT2ATMIGD3PDE1BPTPN2 | |
| SCHEMBL25495987 | 0.82 | TMPRSS2 (0.41) | ALDH1A1LGALS3SMN1; SMN2 | |
| SCHEMBL25495980 | 0.78 | TMPRSS2 (0.36) | LGALS3 | |
| SCHEMBL26298122 | 0.75 | ADORA1 (0.57) | — | |
| SCHEMBL18490384 | 0.74 | GALR3 (0.41) | TMIGD3LGALS3 | |
| SCHEMBL25495999 | 0.74 | TMPRSS2 (0.32) | — | |
| SCHEMBL25496003 | 0.73 | PDE4B (0.33) | ALDH1A1MAPTHTTSMN1; SMN2 | |
| SCHEMBL18490517 | 0.73 | TYMP (0.40) | ALDH1A1TMIGD3RETKDR | |
| SCHEMBL25912544 | 0.71 | TMPRSS2 (0.43) | LGALS3HTT | |
| SCHEMBL18510821 | 0.70 | TTK (0.36) | ALDH1A1TMIGD3NPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3724205-A1 | CYCLIC DINUCLEOTIDES AS STING AGONISTS | Janssen Biotech, Inc. (US) | 2020-10-21 | — | — | EP | disclosed |
| WO-2019118839-A1 | CYCLIC DINUCLEOTIDES AS STING AGONISTS | JANSSEN BIOTECH, INC. (US) | 2019-06-20 | — | — | WO | disclosed |