Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.39 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.39 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.39 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.39 |
| ▸ | LGALS7; LGALS7B | P47929 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.39 |
| ▸ | HK1 | P19367 | 1/20 | 0.39 |
| ▸ | HK2 | P52789 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25495980 | 0.85 | TMPRSS2 (0.36) | TMPRSS2ADORA1ADORA3ADORA2AADORA2B | |
| SCHEMBL16708473 | 0.85 | TMPRSS2 (0.49) | TMPRSS2ADORA1ADORA3ADORA2AADORA2B | |
| SCHEMBL18490384 | 0.85 | GALR3 (0.41) | TMPRSS2ADORA1ADORA3LGALS9LGALS1 | |
| SCHEMBL25495792 | 0.82 | ADORA3 (0.49) | ADORA1ADORA3ADORA2ALGALS9LGALS1 | |
| SCHEMBL21063348 | 0.82 | ALDH1A1 (0.37) | LGALS3ALDH1A1SMN1; SMN2 | |
| SCHEMBL25496003 | 0.78 | PDE4B (0.33) | TMPRSS2TP53TDP1ALDH1A1LMNA | |
| SCHEMBL18510821 | 0.78 | TTK (0.36) | TMPRSS2ADORA3TDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL25495999 | 0.78 | TMPRSS2 (0.32) | TMPRSS2TDP1 | |
| SCHEMBL16708477 | 0.77 | TMPRSS2 (0.47) | TMPRSS2ADORA1ADORA3ADORA2AADORA2B | |
| SCHEMBL22569958 | 0.77 | TSHR (0.51) | ADORA1ADORA3ADORA2AADORA2BTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230146410-A1 | CYCLIC DINUCLEOTIDES AS STING AGONISTS | JANSSEN BIOTECH INC (US) | 2023-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230146410-A1 | CYCLIC DINUCLEOTIDES AS STING AGONISTS | STING1, CGAS, MAVS | TMPRSS2 3340/4885ADORA1 218/4885ADORA3 384/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.