Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.47 |
| ▸ | SPR | P35270 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HPGDS | O60760 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 4/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13490414 | 0.86 | MAPK1 (0.46) | MAPK1 | |
| SCHEMBL17645765 | 0.86 | MAPK1 (0.57) | MAPK1KDM4EL3MBTL1SPRRAB9A | |
| SCHEMBL25953854 | 0.86 | MAPK1 (0.57) | MAPK1KDM4EL3MBTL1SPRRAB9A | |
| SCHEMBL20400835 | 0.82 | MAPK1 (0.53) | MAPK1KDM4EL3MBTL1SPRRAB9A | |
| SCHEMBL21098093 | 0.81 | P4HA1 (0.53) | ALDH1A1MAPT | |
| SCHEMBL21063473 | 0.79 | PDK1 (0.32) | — | |
| SCHEMBL15984766 | 0.78 | MAPK1 (0.49) | MAPK1KDM4EL3MBTL1SPRRAB9A | |
| SCHEMBL29318687 | 0.77 | — | — | |
| SCHEMBL31601627 | 0.77 | MAPK1 (0.54) | MAPK1KDM4EL3MBTL1SPRRAB9A | |
| SCHEMBL15878472 | 0.77 | MAPK1 (0.54) | MAPK1KDM4EL3MBTL1SPRRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019118612-A1 | TARGETING COMPOUNDS | ZAFGEN, INC. (US) | 2019-06-20 | — | — | WO | disclosed |